Study of IMGN632 in Patients With Relapse/Refractory AML, BPDCN, ALL, Other CD123+ Hem Malignancies

Complete Title: A Phase 1/2, Multi-center, Open-Label Study of IMGN632 Monotherapy Administered Intravenously in Patients with CD123-positivie Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies
Trial Phase: I/II
Investigator: Roland Walter, MD

This is an open-label, multi-center, Phase 1/2 study to determine the MTD and assess the safety, tolerability, PK, immunogenicity, and preliminary anti-leukemia activity of IMGN632 when administered as monotherapy to patients with CD123+ disease. The study is currently enrolling eligible AML, BPDCN and ALL patients.

Keywords:
  • Leukemia, Acute Myeloid (AML)
  • Leukemia
  • Leukemia, Lymphoid
  • Myelodysplastic-Myeloproliferative Diseases
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I/II
Roland Walter, MD
RG1005597
NCT03386513
A Phase 1/2, Multi-center, Open-Label Study of IMGN632 Monotherapy Administered Intravenously in Patients with CD123-positivie Acute Myeloid Leukemia and Other CD123-positive Hematologic Malignancies
Leukemia, Acute Myeloid (AML)
Leukemia
Leukemia, Lymphoid
Myelodysplastic-Myeloproliferative Diseases