Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Complete Title: PHASE 1/2 STUDY OF BLU-451 IN ADVANCED CANCERS WITH EGFR EXON20 INSERTION MUTATIONS
Trial Phase: I/II
Investigator: Christina Baik

This is a Phase 1/2, open-label study of the safety, pharmacokinetics (PK), pharmacodynamics, and anti-tumor activity of single-agent BLU-451. All patients will receive BLU-451 as a single agent administered once daily (QD) or twice daily (BID) on a 21-day treatment cycle.

Keywords:
  • Lung Cancer
  • Neoplasms
  • Lung Carcinoma, Non-Small-Cell (NSCLC)
  • Neoplasms, Nerve Tissue
  • Adenocarcinoma
  • Neoplasms, Bronchial
  • Respiratory Tract Diseases
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Adult
I/II
Christina Baik
RG1122465
NCT05241873
PHASE 1/2 STUDY OF BLU-451 IN ADVANCED CANCERS WITH EGFR EXON20 INSERTION MUTATIONS
Lung Cancer
Neoplasms
Lung Carcinoma, Non-Small-Cell (NSCLC)
Neoplasms, Nerve Tissue
Adenocarcinoma
Neoplasms, Bronchial
Respiratory Tract Diseases