FHD-609 in Subjects With Advanced Synovial Sarcoma or Advanced SMARCB1-Loss Tumors

Complete Title: A PHASE 1, MULTICENTER, OPEN-LABEL, DOSE ESCALATION AND EXPANSION STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND CLINICAL ACTIVITY OF INTRAVENOUSLY ADMINISTERED FHD-609 IN SUBJECTS WITH ADVANCED SYNOVIAL SARCOMA
Trial Phase: I
Investigator: Michael Wagner, MD

This Phase 1, multicenter, open-label, dose escalation and expansion study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of FHD-609 given intravenously in subjects with advanced synovial sarcoma or advanced SMARCB1-loss tumors.

Keywords:
  • Sarcoma, Synovial
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Adult
Pediatric
I
Michael Wagner, MD
RG1122014
NCT04965753
A PHASE 1, MULTICENTER, OPEN-LABEL, DOSE ESCALATION AND EXPANSION STUDY TO ASSESS THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND CLINICAL ACTIVITY OF INTRAVENOUSLY ADMINISTERED FHD-609 IN SUBJECTS WITH ADVANCED SYNOVIAL SARCOMA
Sarcoma, Synovial