Abemaciclib in Treating Patients With Advanced, Refractory, and Unresectable Digestive System Neuroendocrine Tumors

Complete Title: A Phase 2 Trial of the CDK4/6 Inhibitor Abemaciclib in Patients with Advanced and Refractory Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors (GEP NETs)
Trial Phase: II
Investigator: David Zhen

This phase II trial studies how well abemaciclib works in treating patients with digestive system neuroendocrine tumors that have spread to other places in the body, do not respond to treatment, and cannot be removed by surgery. Abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Keywords:
  • Neuroendocrine Tumor
  • Neoplasms
  • Carcinoid Tumor
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II
David Zhen
RG1004456
NCT03891784
A Phase 2 Trial of the CDK4/6 Inhibitor Abemaciclib in Patients with Advanced and Refractory Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors (GEP NETs)
Neuroendocrine Tumor
Neoplasms
Carcinoid Tumor