A Study to Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome

Complete Title: An Open-Label, Multicenter Phase 1/1b Study to Characterize Safety, Tolerability, Preliminary Antitumor Activity, Pharmacokinetics, and Pharmacodynamics of Enitociclib (VIP152) Monotherapy or Combination Therapy in Subjects with High-Risk Chronic Lymphocytic Leukemia or Richter Syndrome
Trial Phase: I
Investigator: Mazyar Shadman

Determine the safety, tolerability, pharmacokinetics, maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of VIP152 in patients with Chronic Lymphocytic Leukemia (CLL) or Richter Syndrome

Keywords:
  • Leukemia, Chronic Lymphocytic (CLL)
  • Lymphoma, Non-Hodgkin (NHL)
  • Richter Syndrome
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Adult
I
Mazyar Shadman
RG1122165
NCT04978779
An Open-Label, Multicenter Phase 1/1b Study to Characterize Safety, Tolerability, Preliminary Antitumor Activity, Pharmacokinetics, and Pharmacodynamics of Enitociclib (VIP152) Monotherapy or Combination Therapy in Subjects with High-Risk Chronic Lymphocytic Leukemia or Richter Syndrome
Leukemia, Chronic Lymphocytic (CLL)
Lymphoma, Non-Hodgkin (NHL)
Richter Syndrome