A Study of NKT2152, a HIF2a Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Complete Title: A PHASE 1/2, OPEN LABEL DOSE-ESCALATION AND EXPANSION TRIAL OF NKT2152, AN ORALLY ADMINISTERED HIF2α INHIBITOR, TO INVESTIGATE SAFETY, PHARMACOKINETICS, PHARMACODYNAMICS AND CLINICAL ACTIVITY IN PATIENTS WITH ADVANCED CLEAR CELL RENAL CELL CARCINOMA
Trial Phase: I/II
Investigator: Evan Hall

The goal of the Phase 1 portion is to identify the maximum tolerated dose (MTD) and/or the recommended Phase 2 Dose (RP2D) of NKT2152. The Phase 2 portion will evaluate the efficacy of NKT2152 in ccRCC.

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Adult
I/II
Evan Hall
RG1122075
NCT05119335
A PHASE 1/2, OPEN LABEL DOSE-ESCALATION AND EXPANSION TRIAL OF NKT2152, AN ORALLY ADMINISTERED HIF2α INHIBITOR, TO INVESTIGATE SAFETY, PHARMACOKINETICS, PHARMACODYNAMICS AND CLINICAL ACTIVITY IN PATIENTS WITH ADVANCED CLEAR CELL RENAL CELL CARCINOMA