Lee D. Cranmer, MD, PhD, FACP

Lee D. Cranmer, MD, PhD, FACP

Lee D. Cranmer, MD, PhD, FACP

  • Director of Sarcoma Medical Oncology, Fred Hutch
  • Program Director, Bob and Eileen Gilman Family Sarcoma Research Program, Fred Hutch
  • Professor, Clinical Research Division, Fred Hutch
  • Professor, Division of Hematology and Oncology, University of Washington School of Medicine

Medical Oncology

“You are more than a patient: You are a critical partner in our research efforts. If we hope to improve cancer care, it will only be by working together.”

— Dr. Cranmer

How do you partner with your patients?

I believe in a team-based approach to cancer care, with you at the center of the team. You are also a vital partner in our scientific work, as well as the direct beneficiary of our past and current laboratory research and clinical trials. Although most discoveries lead to only incremental improvements, I’ve been honored to participate in research that has been groundbreaking in its impact on the people we care for.

What made you want to practice oncology?

Several of the mentors and role models in my early life were physicians, and I always knew I wanted to work in a field where my efforts would directly improve the world. While I was a medical resident at the Mayo Clinic, I worked in the cancer ward and quickly realized there were unmet needs for people with cancer, which made me want to continue working with them to see how I could help. I believe that immunotherapy will provide a means to treat the disease more effectively and even prevent it in some cases. I expect to make this the focus of the rest of my career.

Provider Background

Area of Clinical Practice

As the director of Sarcoma Medical Oncology, my expertise is in the clinical management of sarcomas, a rare kind of cancer that grows in connective tissue — cells that connect or support other kinds of tissue in your body. I am focused on supporting and expanding sarcoma research collaborations at Fred Hutchinson Cancer Research Center and UW Medicine, including the development of local clinical trials, involvement in national clinical trials, the teaching and mentoring of hematology-oncology fellows and community-outreach activities.

Skin cancers
I treat patients with melanoma and non-melanoma skin cancers. I’ve been directly involved in the design or execution of over 70 institutional, industry and national cooperative group-sponsored therapeutic clinical trials for melanoma and sarcoma patients, in addition to phase 1 solid tumor protocols. These have included trials of molecularly targeted therapies and immune-boosting therapies, such as immune checkpoint inhibitors.

Diseases Treated

Brain Metastases 


Non-Melanoma Skin Cancer 

Skin Cancer

Immunotherapy of Cancer

Merkel Cell Carcinoma





Education, Experience and Certifications

Undergraduate Degree
Harvard University

Medical Degree
University of California, San Diego

Mayo School of Graduate Medical Education, Internal Medicine

University of Arizona College of Medicine, Medical Oncology

Board Certification
Medical Oncology, 2004, 2014; Internal Medicine, 2001, 2011, American Board of Internal Medicine

PhD, University of California, San Diego; MSc, Liverpool School of Tropical Medicine; Master, University of Liverpool; MPH, University of Arizona; Teaching Appointment, University of Arizona


All news
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Six researchers receive $3.5 million in grants from Kuni Foundation Funds will support innovative high-risk/high-reward projects across Fred Hutchinson Cancer Center/University of Washington/Seattle Children’s Cancer Consortium with the potential to revolutionize care February 27, 2023
7 skin cancer myths — debunked Experts take on base tans and other ‘complete baloney’ standing in the way of skin health August 2, 2017

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you. 

Find a Clinical Trial Led by Lee D. Cranmer


Many of our Fred Hutch physicians conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written.

View Lee D. Cranmer's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with providers.

Email media@fredhutch.org or call 206.667.2210