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Stories tagged 't cell therapy'

Revealing a new way that cancer can evade immunotherapy — and, maybe, how to stop it

How a new technology solved a mystery and honors one man’s legacy

Sept. 24, 2018 | by Susan Keown / Fred Hutch News Service

Before his aggressive cancer took his life, he donated his tissue samples to research. Now scientists think that new insights from his cells could save lives.

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Squelching ovarian cancer: the not-so-silent killer

The search continues for new biomarkers, better outcomes and, yes, cures for this deadly disease

Sept. 17, 2018 | By Diane Mapes / Fred Hutch News Service

September is Ovarian Cancer Awareness Month, but Fred Hutch researchers are working year-round to find ways to detect the disease early and shut it down for good. Read on for a handful of ovarian cancer research highlights.

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Want to make better T-cell therapies? First, figure out how they work.

New study maps out activities, effects of widely used components in cellular immunotherapies

Aug. 21, 2018 | By Susan Keown / Fred Hutch News Service

This work "gives us a direction" to create better, next-gen versions of this type of cancer immunotherapy, called CAR T-cell therapy, the researchers said.

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Nanoparticles open doors to cancer-fighting CAR T cells

Tiny liposome-based drug carriers make tumors more vulnerable to targeted immunotherapy

July 2, 2018 | By Sabrina Richards / Fred Hutch News Service

Scientists at Fred Hutchinson Cancer Research Center have developed a cheap way to make cancers temporarily vulnerable to immune attack using liposome-based nanoparticles to carry immune-boosting drugs deep into tumors.

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His immune system eradicated his melanoma. Could other patients’ bodies be taught to do the same thing?

How one man’s T cells are guiding the development of next-gen immunotherapies

June 19, 2018 | by Susan Keown / Fred Hutch News Service

Chris Pope's immune system eradicated his stage 4 melanoma on an immunotherapy clinical trial. Is it possible to genetically reprogram other patients' to do the same thing?

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Tinkering with T cells

How researchers are tweaking engineered immune cells’ cancer-targeting receptors — and why it matters

May 15, 2018 | By Susan Keown / Fred Hutch News Service

These immune cells are the cornerstone of emerging cancer therapies. And their unimaginably tiny, cancer-targeting molecular weapons — their receptors — are the focus of intense scientific tinkering.

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