How the virus leapt from monkeys to chimps to humans, and why it doesn’t happen more often
Sept. 25, 2015
| By Dr. Rachel Tompa / Fred Hutch News Service
A new study on the evolutionary biology of HIV, simian immunodeficiency virus (SIV) and chimp genes by Fred Hutch virologist Dr. Michael Emerman sheds light on how a critical immune blockade may have been breached, just once, to allow the HIV precursor to leap from monkeys to chimps.
Emerman, Malik study uncovers ability of some HIV-related viruses to defeat primate cellular-defense system SAMHD1 protein
Feb. 6, 2012
Using a combination of evolutionary biology and virology, Fred Hutchinson Cancer Research Center scientists have traced the birth of the ability of some HIV-related viruses to defeat a newly discovered cellular-defense system in primates.