Discovery could lead to the development of a biomarker-based test in lieu of neck surgery
May 9, 2011
| By Dean Forbes
For the first time, Fred Hutchinson Cancer Research Center scientists have identified genes that signal when oral cancer has spread to lymph nodes in the neck. If confirmed by additional research, the discovery of this four-gene set could lead to the development of a biomarker-based test of the tumor that could help physicians determine whether oral squamous cell carcinoma has spread and therefore become more deadly. The findings appear in the April 15 issue of Clinical Cancer Research.
When cancer has spread to lymph nodes, MRI could determine need for radiation therapy
Sept. 29, 2008
In a study of 167 patients who underwent radiation therapy for invasive breast cancer after surgical staging of their tumors, physician researchers at the Seattle Cancer Care Alliance and University of Washington Medical Center found that the tumors’ physiological information shown on MRI scans correlated with surgical findings of cancer having spread to lymph nodes.