Discoveries may result in biomarker test for facioscapulohumeral muscular dystrophy, a disease that initially affects the skeletal muscles of the face, scapula and upper arms
Jan. 30, 2012
| By Dean Forbes
Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, an international team of researchers led by the Hutchinson Center's Dr. Stephen Tapscott has identified the genes and proteins that damage muscle cells, as well as the mechanisms that can cause the disease.
Discovery could lead to the development of a biomarker-based test in lieu of neck surgery
May 9, 2011
| By Dean Forbes
For the first time, Fred Hutchinson Cancer Research Center scientists have identified genes that signal when oral cancer has spread to lymph nodes in the neck. If confirmed by additional research, the discovery of this four-gene set could lead to the development of a biomarker-based test of the tumor that could help physicians determine whether oral squamous cell carcinoma has spread and therefore become more deadly. The findings appear in the April 15 issue of Clinical Cancer Research.
Finding sheds light on protein’s part in cell behavior
Sept. 27, 2010
| By Colleen Steelquist
Researchers in the Fred Hutchinson Cancer Research Center Basic Sciences Division’s Eisenman Lab have discovered a novel function of a cancer-causing gene known as Myc, which is critically important in the progression of many types of cancer. Previous studies of the Myc protein have shown that it regulates gene expression in the nucleus.
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