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Stories tagged 'fruit fly genetics'

Fruit fly study IDs missing links in fat-signaling system

Hormone alerts brain to fat-storage status, but its packaging system goes awry in obesity

Oct. 9, 2017 | By Rachel Tompa / Fred Hutch News Service

A new study uncovers links in the fat-brain connection — in fruit flies. Yes, fruit flies have fat too. Just not very much.

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The sixth samurai: Finding a gene that divides one species from another

How six male flies — among more than 300,000 females — led to the discovery of an evolution-driving gene

Dec. 17, 2015 | By Dr. Rachel Tompa / Fred Hutch News Service

Researchers at Fred Hutch and the University of Utah have discovered a gene that divides one species of fruit fly from another, solving a century-old evolutionary riddle.

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Q&A: How evolutionary biologists got lucky with a sperm discovery

Drs. Harmit Malik and Mia Levine on a male fruit fly protein necessary for embryo survival

July 7, 2015 | By Dr. Rachel Tompa / Fred Hutch News Service

Gestation has traditionally been viewed as the mother’s domain, with dad doing little more than depositing his half of the genome. Now, a new study in fruit flies pinpoints a protein in sperm that regulates embryos’ earliest cell divisions.

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Study reveals how cells’ nuclei keep their shape

Scientists discover a protein that keeps cellular nuclei from shriveling, a hallmark of old age and the premature-aging disease progeria

March 5, 2015 | By Rachel Tompa / Fred Hutch News Service

Scientists at Fred Hutchinson Cancer Research Center have found a protein that helps shape the nucleus, a special compartment within cells that houses and controls genetic information. When cells are missing that protein, known as Wash, nuclei lose their classic plump shape and become wrinkled and puckered. Nuclei pucker in the natural aging process and in certain diseases including progeria, a rare and fatal genetic disorder that dramatically speeds up aging. Whether Wash plays a role in progeria or aging is still unclear, but these findings are an intriguing hint that it might, said Dr. Susan Parkhurst, a biologist at Fred Hutch.

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Discovery in fruit flies may provide insights into some poor prognosis leukemias

Finding from the Fred Hutchinson Cancer Research Center’s Basic Sciences Division newly identifies key protein function, potential therapeutic target

Jan. 14, 2013 | By Colleen Steelquist

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