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Stories tagged 'clinical research'

How to boost cancer clinical trial participation

New study suggests loosening strict comorbidity criteria would open trials to thousands of previously exempt patients

Jan. 10, 2019 | By Diane Mapes / Fred Hutch News Service

Low clinical trial participation is a problem that’s plagued cancer research for decades, with most estimates putting adult cancer patient involvement at less than 5 percent. Fred Hutch's Dr. Joseph Unger, a biostatistician whose research focuses on improving access to trials, led a new study on how comorbidities squelch patient participation -- and what we might be able to do about it.

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How new drugs become available to more patients

Filling in the unknowns on the balance between risk and benefit

Feb. 9, 2018 | by Susan Keown / Fred Hutch News Service

Often, new drugs are only approved to treat patients with advanced disease. But that can change as evidence accrues on the drugs’ risks and benefits.

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New insights into CAR T-cell therapy's potential side effects

Detailed study of cytokine release syndrome and neurologic toxicities could help make emerging cancer immunotherapies safer

Dec. 11, 2017 | By Fred Hutch staff

Detailed studies of two potential side effects of an emerging cancer immunotherapy could eventually help make this strategy, CAR T-cell therapy, safer for patients. The studies examined cytokine release syndrome and neurologic toxicities.

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