Hutch News

Hutch News

Stories tagged 'chimeric antigen receptor'

Tinkering with T cells

How researchers are tweaking engineered immune cells’ cancer-targeting receptors — and why it matters

May 15, 2018 | By Susan Keown / Fred Hutch News Service

These immune cells are the cornerstone of emerging cancer therapies. And their unimaginably tiny, cancer-targeting molecular weapons — their receptors — are the focus of intense scientific tinkering.

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First systematic study of infections after CAR T-cell therapy

“Benchmark” research could help reduce complications of emerging immunotherapy

Nov. 6, 2017 | by Susan Keown / Fred Hutch News Service

The first detailed study of infections after CAR T-cell therapy could help researchers improve the safety of this emerging type of genetically engineered cell therapy for cancer.

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Mourning the loss of Dr. Oliver 'Ollie' Press

Lymphoma physician-scientist, leader and mentor made lifesaving contributions to the development of targeted cancer therapies

Oct. 2, 2017 | by Susan Keown / Fred Hutch News Service

Dr. Oliver Press died of complications from glioma, a brain cancer. Press was a physician-scientist who made foundational contributions to the development of targeted therapies for blood cancers.

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Forum at Fred Hutch focuses on the hottest developments in cancer immunotherapy

Immune-based treatments move from the fringes to the spotlight

June 16, 2017 | By Susan Keown / Fred Hutch News Service

What's new in cancer immunotherapy? Five hot topics, from new combination therapies to cost.

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Dissolving implant could bring immunotherapy to solid tumors

A biopolymer sponge delivers cancer-shrinking T-cell therapy in preclinical study

April 24, 2017 | By Sabrina Richards / Fred Hutch News Service

A dissolving scaffold developed by Dr. Matthias Stephan delivers engineered anti-tumor immune cells to crowded masses of tumor cells and recruits the native immune system to mount a second-wave attack on the cancer.

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Tiny tech reprograms immune cells to fight cancer

Nanoparticles turn immune cells into leukemia-fighting powerhouses while they’re still inside the body

April 17, 2017 | By Sabrina Richards / Fred Hutch News Service

Dr. Matthias Stephan has designed nanoparticles that have the potential to make cellular immunotherapy quicker, cheaper, easier to administer and more widely available, by carrying anti-cancer genes to immune cells still inside the body.

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