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Hutch News

Stories tagged 'chimeric antigen receptor'

Dissolving implant could bring immunotherapy to solid tumors

A biopolymer sponge delivers cancer-shrinking T-cell therapy in preclinical study

April 24, 2017 | By Sabrina Richards / Fred Hutch News Service

A dissolving scaffold developed by Dr. Matthias Stephan delivers engineered anti-tumor immune cells to crowded masses of tumor cells and recruits the native immune system to mount a second-wave attack on the cancer.

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Tiny tech reprograms immune cells to fight cancer

Nanoparticles turn immune cells into leukemia-fighting powerhouses while they’re still inside the body

April 17, 2017 | By Sabrina Richards / Fred Hutch News Service

Dr. Matthias Stephan has designed nanoparticles that have the potential to make cellular immunotherapy quicker, cheaper, easier to administer and more widely available, by carrying anti-cancer genes to immune cells still inside the body.

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Patients with advanced lymphoma in remission after T-cell therapy

New study: 7 of 11 trial participants who got two-drug combination chemo plus intermediate dose of engineered T cells went into complete remission

Sept. 7, 2016 | By Susan Keown / Fred Hutch News Service

Seven of 11 trial participants who got a two-drug combination chemo plus intermediate dose of engineered T cells went into complete remission, a new study found.

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When do we say cure?

A loaded word for cancer patients, but researchers view ‘cure’ through lens of statistics

July 8, 2016 | By Rachel Tompa / Fred Hutch News Service

An individual patient may not hear the word "cure" on their oncologist's lips, but that doesn't mean the word has no meaning to researchers. It's just that it's very difficult to apply it to an individual person.

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93 percent of advanced leukemia patients in remission after immunotherapy

‘Exciting’ but early results from trial of engineered immune cells

April 25, 2016 | By Susan Keown / Fred Hutch News Service

After her immune cells were genetically engineered to target her cancer, Kristin Kleinhofer's leukemia disappeared. The trial was her and her family's 'last hope'.

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