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Stories tagged 'aging'

How the immune system’s key organ regenerates itself

Watch: Hutch researcher discusses harnessing the thymus’s knack for self-repair to boost immune function and help patients

Jan. 12, 2018 | By Susan Keown (text) and Robert Hood (video) / Fred Hutch News Service

Dr. Jarrod Dudakov's discoveries about thymus regeneration could lead to new therapies to improve immune system function in old age and make immunotherapies more effective.

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On the other side of tragedy

People who endure life-changing stress seem to gain resilience — and think they look younger: study

Nov. 18, 2015 | By Bill Briggs / Fred Hutch News Service

Weathering life’s darkest storms and deepest traumas may equip some older adults with the internal armor to better cope with daily aggravations.

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Study reveals how cells’ nuclei keep their shape

Scientists discover a protein that keeps cellular nuclei from shriveling, a hallmark of old age and the premature-aging disease progeria

March 5, 2015 | By Rachel Tompa / Fred Hutch News Service

Scientists at Fred Hutchinson Cancer Research Center have found a protein that helps shape the nucleus, a special compartment within cells that houses and controls genetic information. When cells are missing that protein, known as Wash, nuclei lose their classic plump shape and become wrinkled and puckered. Nuclei pucker in the natural aging process and in certain diseases including progeria, a rare and fatal genetic disorder that dramatically speeds up aging. Whether Wash plays a role in progeria or aging is still unclear, but these findings are an intriguing hint that it might, said Dr. Susan Parkhurst, a biologist at Fred Hutch.

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