Laboratory manipulation of the AIDS-causing virus reveals evolutionary ‘dead-ends’
June 1, 2017
| By Rachel Tompa / Fred Hutch News Service
Fred Hutch researchers have created a library containing millions of mutant HIV viruses. Some of these mutants are very good at infecting human cells, no different from their “natural” viral ancestor. Some of them are worse. Together, they can teach researchers something important about HIV in humans.
GeekWire Award finalists include Bezos Family Immunotherapy Clinic and Nohla Therapeutics, among others; Scientists read infection history in immune genes; and two Hutch faculty members in final class of Kimmel Scholars.
Group of 12 high-risk patients who received engineered T cells after bone marrow transplant still in remission after more than two years
Dec. 5, 2016
| By Susan Keown / Fred Hutch News Service
For patients with high-risk acute myeloid leukemia, relapse after bone marrow transplant signals a low chance of survival. But results from a small trial of genetically engineered immune cells show promise for keeping these patients out of danger: Of the 12 AML patients who received this experimental T-cell therapy after a transplant put their disease in remission, all are still in remission after a median follow-up of more than two years.