BBE Leadership

Vaccine and Infectious Disease Division

Leadership

Program Head, Biostatistics, Bioinformatics and Epidemiology

Dr. Peter Gilbert is a Full Member in the Vaccine and Infectious Disease Division and program head of BBE as well as a member of the VIDD Executive Committee (EC). In his BBE leadership role, he guides the overall vision of the program while collaborating with junior faculty, young investigators, and graduate students.

Dr. Gilbert is also a full member in the Public Health Sciences Division of Fred Hutch and a Research Professor in the Department of Biostatistics at the University of Washington. As Principal Investigator of the statistical center for the HIV Vaccine Trials Network (HVTN), his research focuses on the statistical design and analysis of vaccine efficacy trials, with emphasis on assessing immune correlates of vaccine-induced protection, including the sieve analysis of pathogen sequences infecting trial volunteers. This research contributes to general areas of statistical methods research including surrogate endpoint assessment, causal inference, survival analysis and efficient randomized trial design, with application to vaccine efficacy trials for a variety of pathogens. Collaborating with many investigators from the Thai Ministry of Health, US Military HIV Research Program, Gates Foundation, CHAVI-ID, and the HVTN, Dr. Gilbert provided biostatistical leadership for the RV144 ‘Thai trial’ immune correlates and sieve studies that helped develop a process for immune correlates discovery.
 

Rafael Gottardo, PHD

Associate head of the Biostatistics, Bioinformatics and Epidemiology

Dr. Gottardo is a full member and associate head of the Biostatistics, Bioinformatics and Epidemiology program of the Vaccine and Infectious Disease Division. As part of his leadership role, he helps shape the role of biostatistics and computational biology within VIDD to guide the overall mission of our division.

Within VIDD, he is currently Principal Investigator of the Vaccine and Immunology Statistical Center of the Collaboration for AIDS Vaccine Discovery (CAVD) and Global Health Vaccine Accelerating Platform (GH-VAP) funded by the Bill and Melinda Gates Foundation, where his group contributes statistical and computational methods, data tools, and data analysis for assessing immunogenicity of vaccine candidates with a variety of immunological assays and identifying novel correlates of protection.

Dr. Gottardo also leads the high-dimensional and high-throughput quantitative assay unit of the HIV Vaccine Trials Network (HVTN) funded by the National Institutes of Health, where his group contributes to the analysis and interpretation of high-dimensional assay data (e.g., flow cytometry, CyTOF, single-cell genomics). He plays an important role in the flow cytometry community via his active role in the Flow Informatics and Computational Cytometry Society, the Bioconductor project, and the Flow Cytometry Critical Assessment of Population (FlowCAP) project. Dr. Gottardo also plays an important role within the Human Immunology Project Consortium where he leads the development of the central database and analysis engine, ImmuneSpace.