Studies

Seattle Vaccine Trials Unit

Studies Open to Enrollment

Photo of young men and women

Photos by iStock

Human Papillomavirus  (HPV) Vaccine Study

We are currently enrolling for a new paid study to see how a persons body reacts when given an existing vaccine, for this study we are using the human papillomavirus (HPV) vaccine. The HPV vaccine we are using is a common licensed vaccine  (Gardasil® 9) used to prevent HPV types that cause several kinds of cancer. Our long term hope is that this study may provide information to help with designing a vaccine for Human Immunodeficiency Virus (HIV) or for other viruses. All participants will receive the HPV vaccine and be compensated for their time and effort.

  • men, women, including transgender individuals
  • 18-26 years old
  • have not previously received an HPV vaccine
  • HIV negative
  • able to commit to study visits for the duration of a study
  • visit the clinic throughout the study (frequency varies depending on the study)

 


HIV Vaccine Studies

We are enrolling for a number of HIV vaccine studies that are being coordinated by the Fred Hutch HIV Vaccine Trials Network. The products used in all our trials are NOT produced from live HIV or from HIV-infected human cells. These study vaccines cannot cause HIV infection. We are looking for:

  • men, women, including transgender individuals
  • 18-55 years old
  • HIV negative
  • able to commit to study visits for the duration of a study
  • visit the clinic throughout the study (frequency varies depending on the study)

 


Mucosal Studies

Mucosal Studies are in progress to gain an understanding of how the mucosal immune system works and  people get infected with HIV through sex.  We are looking at the inner lining, or mucous membrane, of people's anatomy.  This knowledge will enable us to develop better ways to prevent HIV infection. We are looking for:

  • 18 to 40 years old
  • HIV negative
  • able to visit the clinic once
  • for people who menstrate: cycles for the last 6 months
  • willing to allow us to obtain a small amount of tissue from the cervix, vagina or rectum

 


Rhinovirus - The Common Cold Research Study

Rhinoviruses are responsible for causing up to 50 percent of the common colds. We hope that this study may provide information to help with understanding why some people get sick more than others from Rhinovirus. The study will compare the body’s immune system response to the common cold (Rhinovirus) in people who feel like they rarely have cold symptoms vs. those that have symptoms more often. We hope to better understand which responses may be necessary for a vaccine to be successful against the common cold. There will be compensation per visit once enrolled in the study. We are looking for:

  • men, women, including transgender individuals
  • 25 to 60 years old
  • HIV negative
  • with regular contact with children
  • in good general health

 


HIV Cohort Studies

Observational studies help us learn more about the immune system in people.  There are no medications or vaccines given.We are conducting a number of observational, also known as cohort, studies. We are looking for:

  • men, women, including transgender individuals
  • 18 to 60 years old
  • HIV negative and HIV positive
  • able to visit the clinic (frequency depends on the study)