Vaccine and Infectious Disease Division

Immunology

Faculty interests focus on elucidating the immunobiology of infectious and malignant diseases and developing cellular and molecular strategies to manipulate innate and adaptive immunity for the treatment of human diseases. This includes research on infectious diseases that cause or are associated with developing cancer as well as infectious diseases prevalent in immunocompromised individuals, such as transplant patients. Our research expertise spans from bench to bedside and includes basic research studies as well as clinical trials. The knowledge gained in basic research studies is the key to developing new therapeutic approaches and vaccines. Investigating ways to eliminate or control infectious diseases via vaccination is a major goal.

Faculty

Staff Scientist, McElrath Lab, Vaccine and Infectious Disease Division
Research interests include early innate immune responses to HIV vaccines on subsequent adaptive immune responses and systems biology analyses of how immune responses are shaped
Research Associate Professor, Laboratory Medicine, University of Washington
Graduate Faculty, Laboratory Medicine, University of Washington
Director, Center for AIDS Research Immunology Core, University of Washington
Characterizing T cells induced by candidate vaccines using flow cytometry. Developing new assays to evaluate vaccine efficacy with HIV Vaccine Trials Network. Studies include examining T cell function at the single-cell level using advanced flow cytometric techniques; examples include T cell responses to vaccination and to viral infections such as CMV, EBV, HIV, and hepatitis B.
Director for Scientific Affairs, HIV Vaccine Trials Network
Affiliate Professor, Epidemiology and Global Health, University of Washington
The conduct of HIV vaccine trials, novel vaccine strategies, the conduct of clinical trials in resource-poor settings, and factors that help prevent sexual transmission of HIV.
Phone: (206) 667-7938
Fax: (206) 667-7711
Affiliate Assistant Professor, Biostatistics, University of Washington
Statistical problems in biological assays, Biological sequence analysis, Stochastic optimization
Phone: (206) 667-1093
Fax: (206) 667-4378
Associate Director for Laboratory Science, HIV Vaccine Trials Network
Associate Professor, Department of Global Health, University of Washington
Graduate Faculty, Global Health, University of Washington
Elucidating cellular mechanisms for control of HIV replication, Assessing cellular immune responses in HIV vaccine recipients, Teaching and Mentoring Interests, HIV immunology for experts and the public
Professor, Medicine, University of Washington
Adjunct Associate Professor, Microbiology, University of Washington
Director, Infectious Diseases Fellowship Training Program, University of Washington
Determining how changes in microbial communities impact human health; identifying, characterizing, and culturing microbes found in the human genital tract; and associating the reproductive tract microbiome with human disease. Developing molecular diagnostic tests to detect and identify pathogens in immunocompromised hosts such as cancer patients.
Phone: (206) 667-1935
Fax: (206) 667-4411
Affiliate Associate Professor, Statistics, University of Washington
Developing methods and tools for high throughput, high dimensional experiments with applications in vaccine research and immunology; flow cytometry, peptide microarrays, next generation sequencing; Bayesian inference and computation and statistical computing
Phone: (206) 667-4076
Fax: (206) 667-4378
Clinical Trials Physician /Protocol Team Leader, HIV Vaccine Trials Network (HVTN)
Immunology and vaccine design for development of vaccines, especially HIV-1 vaccine
Host-pathogen co-evolution, T-cell and B-cell immunodominance and the effects of immunological history.
Principal Staff Scientist, Vaccine and Infectious Disease Division
Principal Staff Scientist, Public Health Sciences Division
Unit Head, Biostatistical Collaborative Unit for Study Design and Data Analysis, Vaccine Immunology Statistical Center
Research focus include the design and analysis of clinical trials
Phone: (206) 667-5780
Fax: (206) 667-4378
Associate Director for Laboratory Operations, HIV Vaccine Trials Network (HVTN)
Immunologic endpoint determination for experimental vaccines (HIV, pneumococcus, malaria, TB, flu) and Logistics, operations, quality assurance, and assay validation for immunologic evaluation of vaccines in the clinical trial setting
Professor, Laboratory Medicine, University of Washington
Head, Virology Division, University of Washington
Director, Molecular Virology Laboratory, Laboratory Medicine, University of Washington
Clinically important persistent and latent viral infections; curative therapies for latent viral infections ;diagnosis of disease caused by herpesviruses, enterovirus, JC and BK viruses, parvovirus B19, and hepatitis viruses
Phone: (206) 667-6793
Fax: (206) 667-6179
Research Assistant Professor, Global Health, University of Washington
Graduate Faculty, Global Health, University of Washington
Roles of regulatory T cells in modulating anti-viral immunity; anti-viral immunity; vaccine development
Senior Vice President and Director, Vaccine and Infectious Disease Division
Professor of Medicine, University of Washington
Adjunct Professor, Pathobiology, Global Health, and Laboratory Medicine, University of Washington
Research centers on developing an HIV vaccine and investigating the complex relationship between HIV and the immune system and the influence of antiretroviral therapy.
Senior Staff Scientist, Public Health Sciences Division
Research focus includes vaccine clinical trials, SNP analysis, novel statistical methodology, nonparametric methods
Phone: (206) 667-7077
Fax: (206) 667-4378
Affiliate Assistant Professor, Department of Global Health, University of Washington
Faculty Member, Interdisciplinary Program in Pathobiology, University of Washington
Faculty Member, Molecular & Cellular Biology Program, Fred Hutch & University of Washington
Study T cell fate and function in healthy and inflamed tissues and following infection with HIV and manipulate these responses for therapeutic purposes
Phone: (206) 667-2216
Fax: (206) 667-2209
Assistant Member, Clinical Research Division
Assistant Professor, Medicine, University of Washington
Study Physician, UW Virology Research Clinic, University of Washington
Interest in describing the quantitative and dynamical features of human pathogens and immune responses. Most of work to-date is on the pathogenesis of HSV-2 infection but also interested in applying models to optimize viral eradication startegies, and to use models to capture kinetic features of the human microbiome.
Structural molecular immunology and vaccinology: using biophysical approaches to study proteins and interactions mediating or modulating adaptive and innate immune responses
Phone: (206) 667-5587