We submitted an application in May 2015 to request funding to continue the Seattle Cancer Consortium Breast SPORE for five years. From a broad range of projects, we have selected, with the help of our advisory board, timely projects that will most directly impact the field of breast cancer research by aiming to improve therapy and a fourth project that will improve the interpretation of genetic tests for inherited breast cancer.
The investigators in this continuation of the SPORE are on the forefront of research in immunotherapy, tumor microenvironment, cell cycle regulation and genetics.
Of the three projects implementing clinical trials within the SPORE, two will focus on immune strategies to improve treatment for women with triple negative breast cancer and the third proposes a highly novel strategy to exploit cell cycle control for enhancing chemotherapy.
Our population project brings together resources from extensive genetic testing for inherited breast cancer genes and the population followed for over 20 years in the Women’s Health Initiative (WHI) to provide important data on the significance of genetic variants to risk for breast cancer
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