Sara Lindstroem, PhD

Sara Lindstroem, PhD

Assistant Professor, Department of Epidemiology
University of Washington

Education

PhD Genetic Epidemiology, Umea University, 2007
MSc Engineering Physics, Umea University, 2004

Research Focus

My research focuses on understanding the genetic contribution to common complex diseases, with a primary emphasis on cancer and linked traits. By leveraging long-running large population-based studies, I investigate how our genetics and environment affect our risk of developing disease.

Current research projects include studying the shared genetic origin between common cancers and the genetics underlying childhood obesity, breast tissue composition and venous thromboembolism. I am also interested in finding approaches to incorporate information about the functional characteristics of the genome in my studies. Finally, I am involved in several large-scale international collaborations that study the genetics underlying breast and prostate cancer.

Publications

1. Michailidou K, Beesley J, Lindström S, et al. Combined GWAS analysis of more than 120,000 individuals identifies 15 novel susceptibility loci for breast cancer. Nat Genet. 2015 Apr; 47(4):373-80. PMCID: PMC4549775

2. Lindström S, Thompson DJ, Paterson AD, et al. Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk. Nature Commun. 2014 Oct 24; 5:5303. PMCDI: PMC4320806

3. Cao Y, Lindström S, Schumacher F, et al. Insulin-like Growth Factor Pathway Genetic Polymorphisms, Circulating IGF1 and IGFBP3, and Prostate Cancer Survival. J Natl Cancer Inst. 2014 Jun; 106(6): dju085. PMCID: PMC4081624

4. Garcia-Closas M, Couch, FJ, Lindström S, et al. Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet. 2013 Apr;45(4):392-8. PMCID: PMC3771695

5. Campa D1, Kaaks R, Le Marchand L, Haiman CA, Travis RC, Berg CD, Buring JE, Chanock SJ, Diver WR, Dostal L, Fournier A, Hankinson SE, Henderson BE, Hoover RN, Isaacs C, Johansson M, Kolonel LN, Kraft P, Lee IM, McCarty CA, Overvad K, Panico S, Peeters PH, Riboli E, Sanchez MJ, Schumacher FR, Skeie G, Stram DO, Thun MJ, Trichopoulos D, Zhang S, Ziegler RG, Hunter DJ, Lindström S, Canzian F. Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. J Natl Cancer Inst. 2011 Aug 7; 103(16):1252-63. PMCID: PMC3156803

6. Lindström S, Vachon CM, Li J, Varghese J, Thompson D, Warren R, Brown J, Leyland J, Audley T, Wareham NJ, Loos RJ, Paterson AD, Rommens J, Waggott D, Martin LJ, Scott CG, Pankratz VS, Hankinson SE, Hazra A, Hunter DJ, Hopper JL, Southey MC, Chanock SJ, Silva Idos S, Liu J, Eriksson L, Couch FJ, Stone J, Apicella C, Czene K, Kraft P, Hall P, Easton DF, Boyd NF, Tamimi RM. Common variants in ZNF365 are associated with both mammographic density and breast cancer risk. Nat Genet. 2011 Mar; 43(3):185-7. PMCID: PMC3076615

7. Lindström S, Wiklund F, Adami HO, Balter KA, Adolfsson J, Gronberg H. Germ-Line Genetic Variation in the Key Androgen-Regulating Genes Androgen Receptor, Cytochrome P450, and Steroid-5-{alpha}-Reductase Type 2 Is Important for Prostate Cancer Development. Cancer Res. 2006 Nov 15; 66(22):11077-83. PMID: 17108148

Complete List of Published Work in MyBibliography:  https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/49853239/?sort=date&direction=ascending



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Sara Lindstroem, PhD

Contact Information

Phone
(206) 221-3148
Fax
(206) 667-4787
Email
Additional contact

Mail Stop: M4-B874