Flax FX Study

A research study of the effects of flaxseed lignans on colon health.

Why is this study being done?

Colorectal cancer (CRC) is the third most common cancer in the United States and its incidence is rising in younger populations. Diet seems to affect risk for CRC.

Many parts of our diet are processed and modified by the microbes or bacteria in our gut. There are many different types of bacteria in our gut, each one of us has a “community” of different types and amounts of each type.

flax plant and linseed oil

Photo courtesy of Handworker "From flax plant to linseed oil"

When we eat flaxseeds, certain types of bacteria will process them, producing compounds that can then affect our bodies. How much of these compounds are produced by each person depends on the “community” of bacteria in the gut.

Flaxseed and certain nuts contain lignans, compounds that may have health benefits. Gut bacteria can convert the lignans into biologically active compounds that in animals prevent the development of colon cancer. We will study how these biologically active compounds affect colon cell-signaling pathways important to CRC risk.

Results from our study will bridge the current knowledge from animal studies and epidemiologic studies and may help to inform approaches for future CRC prevention.

What should you do if you are interested in participating?

If you are interested in participating, complete the initial questionnaire and return it to us. We will contact you to let you know whether you are eligible to attend an orientation session about the study.

* FLAX FX Brochure
Detailed information about the study and participant activities.
* FlaxFX Questionnaire
You will need to fill out and send to us if you are interested in participating.

If you would like, we can send you the brochure and the initial questionnaire via mail (click here) or email (click here).