IRIS Study

Cancer Epidemiology Research Cooperative (CERC)

IRIS Study

A Study of Gynecologic Conditions

IRIS Study Logo

Principal Investigator: Margaret M Madeleine, PhD
Project Coordinator: Lisa G Johnson, PhD
Program Assistant: Christabel Fowler
Study Interviewer: Patty Pride

Contact Information:

     866-352-9525 Toll Free
     206-667-5948 Fax


     The IRIS Study
     Fred Hutchinson Cancer Research Center
     PO Box 19024 (M4-C308)
     Seattle WA  98109-1024

The goal of the IRIS study is to enroll about 1,000 women with certain gynecologic conditions to share their medical history and provide a saliva sample, which contains genetic material. We want to better understand what medical, lifestyle, background, and genetic factors may be related to these conditions.

Who is being asked to participate in the IRIS study?


Women who have had a cervical condition (pre-cancer or cancer) diagnosed between 2005 - 2010 and who live in western Washington state are eligible to participate.  If a woman has not had cancer but had a related condition, she may still be eligible to participate.


Why is participation important?


For the results of the IRIS study to be accurate, it is important that almost every woman selected for the study chooses to participate.  Everyone has a unique medical history.  Although participation is voluntary, progress in cancer research depends on the willingness of the women contacted to get involved.


What does participation in the IRIS study involve?


Women who choose to participate in the IRIS study will be asked to complete a short questionnaire.  The questionnaire will take about 15 minutes to complete.  An additional part of the IRIS study is donation of a saliva sample to provide a small amount of genetic material.  This will require another 5-10 minutes.  Participants will be asked to mail the questionnaire and saliva sample to the Fred Hutch in an envelope that will be provided.


How is confidentiality maintained?


All information collected in the IRIS study is considered strictly confidential.  The questionnaire is coded with a unique study number so names do not need to be included on the form.  Likewise, the saliva sample is coded with a unique study number.  In research reports from this study, information will be grouped and no individual will be personally identifiable.


The funding for this study was provided by a grant to the Fred Hutch.