Diet and Genetic Risk for Prostate Cancer
This study investigates comprehensive measures of diet and dietary supplements with a focus on antioxidants measured by both self-reported and blood based biomarkers of intake in relation to prostate cancer risk among 12,000 participants in the Carotene and Retinol Efficacy Trial (CARET). We also measured polymorphisms in oxidative stress regulatory genes and whether any diet gene interactions modify associations of diet and nutritional biomarkers with prostate cancer risk.
Related Publications
- Genetic variation in myeloperoxidase modifies the association of serum α-tocopherol with aggressive prostate cancer among current smokers.
- Body mass index and prostate cancer risk in the Carotene and Retinol Efficacy Trial.
- Dietary supplement use and prostate cancer risk in the Carotene and Retinol Efficacy Trial.
- Selenium and Prostate Cancer: Analysis of Individual Participant Data From Fifteen Prospective Studies.
- A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk.
- Carotenoids, retinol, tocopherols, and prostate cancer risk: pooled analysis of 15 studies.
- Circulating fatty acids and prostate cancer risk: individual participant meta-analysis of prospective studies.
- Serum phospholipid fatty acids, genetic variation in myeloperoxidase, and prostate cancer risk in heavy smokers: a gene-nutrient interaction in the carotene and retinol efficacy trial.
Marian Neuhouser, PHD, RD
Program Head, Cancer Prevention Program
More Information
Funding Agency:
National Cancer Institute
Contacts:
Diana Lowry dlowry@fredhutch.org
