About the IIRC

Immunotherapy Integrated Research Center (IIRC)

Accelerating Discoveries

Fred Hutch created the Immunotherapy Integrated Research Center (IIRC), to advance our research and increase collaboration across scientific disciplines. The IIRC, directed by Dr. Stanley Riddell, is helping to develop new partnerships, facilitate the recruitment of new team members, and fund early-stage projects to jump-start new ideas. Through the IIRC, the Hutch’s programs in cell therapy, transplant immunology, tumor microenvironment, immune checkpoint regulation, immunogenomics, therapeutic vaccines and more will continue to grow.

The goal: curative therapies for all cancers.

Next-Generation Immunotherapy

Hutch's scientific depth

Through Hutch's robust translational research and clinical programs, our scientists are studying the fundamental immune mechanisms with an aim toward translational to the clinic. They are developing first-in-class immunotherapies and accelerating innovation interdisciplinary science. Experts in fundamental cancer biology, experienced clinicians and immunologists team with leaders in fields like immunobioengineering, cellular and molecular biology, and statistical modeling to learn how current immunotherapies work — or don’t — and develop even better strategies going forward.

Making clinical trials available to patients

To support our patients, Fred Hutch recently opened the Bezos Family Immunotherapy Clinic at Seattle Cancer Care Alliance, our clinical care partner. The clinics skilled staff and the Fred Hutch-based clinical research team are a cornerstone of the IIRC’s clinical research resources. Together, they enables immunotherapy clinical trial participants to be studied intensively to learn why a therapy works or does not in each patient, following the model set by the Nobel Prize–winning Fred Hutch team that developed bone marrow transplantation.

Funding innovative research

The IIRC funds collaborative, multidisciplinary projects in immunotherapy and supports individual Fred Hutch researchers to pursue innovative research ideas. The grant funding is not limited to IIRC participants, but it is open to any Fred Hutch investigators whose research will advance immunotherapy.

Integrated Research Centers

Fred Hutch's Integrated Research Centers (IRC) promote collaboration among Hutch researchers on high impact and innovative projects, and leverage Hutch's unique resources and expertise.