Public Health Sciences Division, Fred Hutch
Dr. Margaret Pepe is a biostatistician and an international expert on the evaluation of tests and biomarkers for disease screening, diagnosis, prognosis and risk prediction. She leads the Diagnostic and Biomarkers Statistical Center at Fred Hutch, which promotes the application of sound statistical methods in the evaluation of diagnostic/prognostic devices and biomarkers. Dr. Pepe has a long record of collaborative research through the Biostatistics Shared Resource at Fred Hutch and is co-principal investigator of the Early Detection Research Network’s Data Management and Coordinating Center. The latter provides logistical, informatics and statistical services to the EDRN to develop, evaluate and validate biomarkers for early cancer detection and risk assessment. In collaboration with EDRN colleagues Dr. Pepe defined a phased approach to biomarker development and the prototype study design for biomarker evaluation that is used by researchers throughout the network.
University of Washington School of Public Health and Community Medicine
Ph.D., Biomathematics, University of Washington, 1986
M.S., Statistics, University of Washington, 1984
B.S., Mathematical Science, University College, Cork, 1981