Margaret Sullivan Pepe, Ph.D.

faculty member

Margaret Sullivan Pepe, Ph.D.

Public Health Sciences Division, Fred Hutch

Fax: 206.667.7004
Mail Stop: M2-8500

Dr. Margaret Pepe is a biostatistician and an international expert on the evaluation of tests and biomarkers for disease screening, diagnosis, prognosis and risk prediction. She leads the Diagnostic and Biomarkers Statistical Center at Fred Hutch, which promotes the application of sound statistical methods in the evaluation of diagnostic/prognostic devices and biomarkers. Dr. Pepe has a long record of collaborative research through the Biostatistics Shared Resource at Fred Hutch and is co-principal investigator of the Early Detection Research Network’s Data Management and Coordinating Center. The latter provides logistical, informatics and statistical services to the EDRN to develop, evaluate and validate biomarkers for early cancer detection and risk assessment. In collaboration with EDRN colleagues Dr. Pepe defined a phased approach to biomarker development and the prototype study design for biomarker evaluation that is used by researchers throughout the network.

Other Appointments & Affiliations

Professor, Biostatistics
University of Washington School of Public Health and Community Medicine


Ph.D., Biomathematics, University of Washington, 1986

M.S., Statistics, University of Washington, 1984

B.S., Mathematical Science, University College, Cork, 1981

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For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with faculty.

Email or call 206.667.2210