Dr. Poorni Manohar studies ways to improve the quality and value of cancer care, especially in lobular and metastatic breast cancer. Her goal is for every patient to receive the best evidence-based care for their particular cancer. She collaborates in this research with the Hutchinson Institute for Cancer Outcomes Research, which aims to reduce the economic and human burdens of cancer. One area of her research focus is the use of imaging, such as positron emission tomography, or PET, to help doctors choose the best treatment for each patient. She also studies how the use and cost of drugs called bone-modifying agents varies between regions. Doctors use these drugs to help strengthen bone in patients whose breast cancers have spread to and damaged the skeleton. She aims to learn how to improve the use of these drugs to maximize patients' quality of life and minimize side effects and financial impacts. Dr. Manohar is also an oncologist, and in the clinic she cares for patients with breast cancer.