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Agenda

All times Pacific Daylight time (PDT-UTC-7)

 

Sunday, October 3, 2021

5:00 p.m. - 7:00 p.m.        Meet & Greet Happy Hour in Sococo Lounge

Monday, October 4, 2021

 8:00 a.m. - 8:30 a.m.          Welcome  |  Joshua T. Schiffer and Elissa J. Schwartz


Session 1: SARS-CoV-2 1 

8:30 a.m. - 9:10 a.m.      Plenary Speaker  |  Stephen Kissler, Harvard T.H. Chan School of Public Health
                                             SARS-CoV-2 viral dynamics from longitudinal surveillance tests: inference and applications

9:10 a.m. - 9:30 a.m.      Budhaditya Chatterjee, Indian Institute of Science Bangalore
                                            Modeling how the interplay between innate immune and CD8 T-cell responses underlies the heterogeneous outcomes of SARS-CoV-2 infection

9:30 a.m. - 9:50 a.m.      Aurélien Marc, French National Institute of Health and Medical Research (Inserm)
                                            Quantifying the relationship between SARS-CoV-2 viral load and infectiousness 

9:50 a.m. - 10:10 a.m.    Ruian Ke, Los Alamos National Laboratory
                                             Modeling of early infection of SARS-COV-2 and the B.1.1.7 variant from densely sampled unvaccinated and vaccinated individuals 

10:10 a.m. - 10:30 a.m.  Break — Meet in Sococo


Session 2: SARS-CoV-2 2

10:30 a.m. - 10:50 am   Ruy M. Ribeiro, Los Alamos National Laboratory
                                            How do we detect more SARS-CoV-2 infected people? Testing strategies informed by viral dynamics 

10:50 a.m. - 11:10 am   Melanie Moses, University of New Mexico 
                                            Spatially distributed infection increases viral load in a computational model of SARS-CoV-2 lung infection

11:10 a.m. - 11:30 am   Naveen Vaidya, San Deigo State University
                                            Modeling Within-Host Dynamics of SARS-CoV-2 Infection in Ferrets

11:30 a.m - 11:50 am    Christopher Brooke, University of Illinois at Urbana-Champaign
                                            Daily longitudinal sampling of SARS-CoV-2 infection in naïve and vaccinated humans reveals tissue compartmentalization and benefits of serial testing.

11:50 a.m. - 12:30 p.m.  Break — Meet in Sococo


Session 3: HIV

12:30 p.m. - 1:10 p.m.   Plenary Speaker  |  Robert F. Siliciano, Johns Hopkins University School of Medicine
                                            HIV decay dynamics: implications for cure

1:10 p.m. - 1:30 p.m.     Lucas Böttcher, Frankfurt School of Finance and Management gGmbH
                                            Clonal population dynamics of HIV-infected cells after administration and cessation of antiretroviral therapy

1:30 p.m. - 1:50 p.m.     Andrea Ramirez, University of Florida
                                            A machine learning approach to predicting immune-mediated viral neuroadaptation in the macaque model of HIV infection

1:50 p.m. - 2:10 p.m.     Steffen Docken, University of New South Wales
                                            Not all virus is produced equally: Characterization of the variability of Simian Immunodeficiency Virus production

2:30 p.m. - 4:30 p.m.     Poster Session 1 — Sococo

5:00 p.m. - 6:00 p.m.     Happy hour/ Breakfast (greetings with Asian Pacific & Australian attendees) — Sococo lounge and common areas

Tuesday, October 5, 2021

8:15 a.m. - 8:30 a.m.  Welcome Joshua T. Schiffer and Elissa J. Schwartz

Session 1: Influenza, other viruses & immunology

8:30 a.m. -9:10 a.m.           Plenary Speaker  |  Wilfred Ndifon, African Institute for Mathematical Sciences (AIMS)
                                                Organizing principles of T-cell immunity, and implications for virus dynamics 

9:10 a.m. - 9:30 a.m.          Emily E. Ackerman, University of Pittsburgh
                                                 Interferon Production Rate is a Major Contributor to Differential Strain-Specific Immunodynamics

9:30 a.m. - 9:50 a.m.          Christian Quirouette, Ryerson University
                                                A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

9:50 a.m. -10:10 a.m.        David Swigon, University of Pittsburgh
                                                Mathematical modeling approaches for in-host immune response to IAV infection

10:10 a.m. - 10:30 a. m.    Break — Meet in Sococo

 

Session 2: Influenza, other viruses & immunology

10:30 a.m. - 10:50 a.m.     Daniel Rüdiger, Max Planck Institute for Dynamics of Complex Technical Systems
                                                Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culture

10:50 a.m. -11:10 a.m       Frederik Graw, Heidelberg University
                                                From local to global control: The interaction of murine cytomegalovirus replication and IFNγ-producing CD4+ T cells in the salivary gland

11:10 a.m. - 11:30 a.m.     Soheil Rastgou Talemi, German Cancer Research Center
                                                Host factors are the key regulators of heterogeneity in dengue virus replication onset and capacity following virus entry into the cell

11:30 a.m. - 11:50 a.m.     Gang Zhao, Helmholtz Center for Infection Research
                                                Delayed type 1 interferon response and the subsequent out-of-sequence signal for T cell induction in non-surviving Ebola infected patients

11:50 a.m. - 12:10 p.m.     Elissa Schwartz, Washington State University
                                                Quantifying in vivo virus dynamics and escape in equine infectious anemia virus (EIAV) infection

12:10 p.m. - 12:40 p.m.     Break — Meet in Sococo


Session 3: Influenza, other viruses & immunology

12:40 p.m. - 1 p.m.            Catherine Byrne, The University of British Columbia
                                               Examining the Dynamics and Spatiotemporal Spread of Primary MCMV Infection

1 p.m .- 1:20 p.m.              Sivan Leviyang, Georgetown University
                                               The Patterns and Functionality of Heterogeneity in the Type I Interferon Response

1:20 p.m. - 1:40 p.m.        Jannatul Ferdous, University of New Mexico
                                               Distributed Processing in Lymph Nodes Supports a Scalable Immune Response

1:40 p.m. - 2 p.m.              Jordan J.A. Weaver, University of Pittsburgh
                                               A Spatial Model of Interferon Signaling and Virus Replication Gives Insights into Plaque Growth Dynamics

2 p.m. - 2:20 p.m.              Ke Li, The University of Melbourne
                                               Modeling the effect of MUC1 on influenza virus infection kinetics and macrophage dynamics

2:30 p.m. - 4:30 p.m.        Poster Session 2 — Sococo

Wednesday, October 6, 2021

8:15 a.m. - 8:30 a.m.    Welcome Joshua T. Schiffer and Elissa J. Schwartz
 

Session 1: Evolution and Methods

8:30  a.m. - 9:10 a.m.    Plenary Speaker  |  Katia Koelle, Emory University
                                            Considering cellular coinfection in within-host viral dynamics and evolution 

9:10 a.m. - 9:30 a.m.      Mélanie Prague, Université de Bordeaux, Inserm, Inria
                                            Fast Automatic Model Building in Nonlinear Mixed Effects Models with SAMBA  

9:30 a.m. - 9:50 a.m.      Gary An, University of Vermont
                                             Becoming bat-man: insights into potential viral-species-agnostic interventions to control viral disease severity from comparative computational modeling between bats                                                   and humans

9:50 a.m. - 10:10 a.m.    Daniel Reeves, Fred Hutchinson Cancer Research Center
                                             Merging viral dynamics and phylodynamics for HIV primary infection

10:10 a.m. - 10:30 a.m.  Break — Meet in Sococo

 

Session 2: Hepatitis and Therapy


10:30 a.m. - 10:50 a.m.  Jérémy Seurat, INSERM IAME UMR 1137 - Université Paris Diderot
                                             Combination of in vivo phage therapy data with in silico model highlights key parameters for treatment efficacy

10:50 a.m. - 11:10 a.m.  Richard Bingham, University of York
                                             A stochastic, multiscale model of Hepatitis C infection reveals the potential of a novel therapeutic interfering particle design

11:10 a.m. - 11:30 a.m.  Fabian Cardozo-Ojeda, Fred Hutchinson Cancer Research Center
                                             Modeling the pharmacokinetics and pharmacodynamics of eCD4Ig in SHIV-infected rhesus macaques

11:30 a.m. - 11:50 a.m.  Ashish Goyal, Pfizer Inc
                                             Modeling HBV DNA and ALT responses observed under an entry inhibitor in HBV monoinfected individuals supports heterogeneity in the infected cell population

11:50 a.m. -12:30 p.m.   Break — Meet in Sococo

 

Session 3: Hepatitis and Therapy

12:30 p.m. - 12:50 p.m.  Bryan T. Mayer, Fred Hutchinson Cancer Research Center 
                                              Optimizing clinical dosing of combination broadly neutralizing antibodies for HIV prevention

12:50 p.m. - 1:10 p.m.     Jay Srinivas, Loyola University Chicago
                                              Mathematical modeling of early hepatitis D virus kinetics in transgenic-hNTCP mice

1:10 p.m. - 1:30 p.m.       Shingo Iwami, Nagoya University
                                              Elimination of intrahepatic cccDNA of patient could be predicted by combination of personal viral markers

1:30 p.m. - 1:50 p.m.       Shoya Iwanami, Nagoya University
                                              Detection of significant antiviral drug effects on COVID-19 with reasonable sample sizes in randomized controlled trials

1:50 p.m. - 2:30 p.m.       Farewell session — Sococo common areas

2:30 p.m. - 3:30 p.m.       Post-workshop Professional Development Session (for trainees)