Biostatistics Seminar Series, February 24, 2021


The Fred Hutch Biostatistics Program hosts seminars featuring presentations by Hutch and outside scientists to share their latest developments and recent research. Each seminar includes an hour-long presentation and discussion during which speakers showcase their work and findings.

This seminar will be held on Zoom due to the COVID-19 pandemic.


Biostatistics Seminar Series: 

“Statistical and computational aspects in the analysis of genomic data from family based designs”

Family based study designs are regaining popularity because large-scale sequencing can help to interrogate the relationship between disease and variants too rare in the population to be detected through any test of association in a conventional case-control study, but may nonetheless co-segregate with disease within families. In addition, family based designs also allow for the assessment of de novo events and parent-of-origin effects. In this presentation, we focus on statistical and computational aspects in the analysis of sequencing data from nuclear families with affected probands and extended multiplex families, with an emphasis on improvements in scalability and new methods for causal variant detection.   

Wednesday, February 24, 2021
Start Time:
12 p.m. PST
Host or Sponsor:
Speaker or Presenter:
Contact Information:
Last Modified, February 03, 2021