Biostatistics Seminar Series, December 7, 2022

The Fred Hutch Biostatistics Program hosts seminars featuring presentations by Fred Hutch and outside scientists to share their latest developments and recent research. Each seminar includes an hour-long presentation and discussion during which speakers showcase their work and findings. 

This seminar will be via Zoom.

Ni Zhao, Ph.D.

PRESENTER:

Ni Zhao, Ph.D.

“Integrative analysis of multiple microbiome datasets”

Recent studies have highlighted the importance of human microbiota in our health and diseases. However, in many areas of research, individual microbiome studies often offer inconsistent results due to the limited sample sizes and the heterogeneity in study populations and experimental procedures. Integrative analysis of multiple microbiome datasets is necessary. However, statistical methods that incorporate multiple microbiome datasets and account for the study heterogeneity are not available in the literature. In this talk, I am going to discuss two recent developments from our lab that aim at integrative analysis of multiple microbiome datasets, one for the analysis of alpha diversity and one for the analysis of beta diversities. We applied these approaches to data from the HIV-reanalysis consortium, a collective effort that obtained all publicly available data on gut microbiome and HIV in December 2017, and obtained a coherent association of gut microbiome with HIV infection, and with MSM status (i.e. men who have sex with men).

Date:
Wednesday, December 07, 2022
Start Time:
12 p.m. PST
Host or Sponsor:
Location:
Hybrid: M4-A805/A817 and Zoom Webinar
Speaker or Presenter:
Ni Zhao, Ph.D.
Contact Information: