Biostatistics Seminar Series, October 16, 2019

Abstract. Causal discoveries are difficult to obtain in the presence of high-dimensional observational datasets. We begin by showcasing how to utilize additional information on covariates to obtain confidence sets of average treatment effect and treatment effect size of a genotype mutation on HIV drug resistance.  We then highlight a new approach for dynamic treatment discovery in the presence of   “poor” data – we do not require propensity score estimation and yet provide treatment effect confidence sets that account for the complete individual history. Lastly, we showcase a new method for directed causal “parent-child” discoveries in the presence of both interventional as well as observational data. We work with Yeast genetic network under wild-type and gene-knockout interventional data. If time permits we will showcase some new results for censored, EHR data.

Joint work with my Ph.D. students: Jue Hou, Denise Rava, Davide Viviano, Yuqian Zhang, and my long-term collaborators: prof. Yinchu Zhu and Ronghui Xu.

Date:
Wednesday, October 16, 2019
Start Time:
12 p.m.
Host or Sponsor:
Biostatistics Program and Translational Data Science IRC
Location:
D1-080/084
Thomas Building
Speaker or Presenter:
Jelena Bradic, Ph.D.
Contact Information:
Last Modified, October 08, 2019