ASH 2023

American Society of Hematology

December 9-12, 2023
Meeting Attendance is In-person or Virtual

 

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Fred Hutchinson Cancer Center’s latest findings on blood and marrow transplantation, cell therapies, precision medicine and more will be featured at the 65th Annual Meeting and Exposition of the American Society of Hematology (ASH).

This year's annual meeting will be held at the San Diego Convention Center in San Diego, California and virtually for those who cannot attend in person.

The ASH meeting provides an invaluable educational experience and the latest on the hottest topics in hematology. Attendees include top minds in the field and a global community of more than 25,000 hematology professionals from every subspecialty.

The meeting features the annual E. Donnall Thomas Lecture, named for the Fred Hutch physician-scientist who was awarded the Nobel Prize in physiology or medicine for his development of bone marrow transplantation. This year, the lecture will be held on Monday, December 11, 2023.

Visit the Fred Hutch booth #3337.

Date:
Saturday-Tuesday, December 09-12, 2023
Location:
San Diego, California
Contact Information:

Read our Media Tip Sheet Highlighting Fred Hutch at ASH

Featured Sessions

Sandhya Panch, MD

Scientific Workshop

Diagnostic Testing in Classical Hematologic Disorders

Presenter: Sandhya R Panch, MD 
Session: Advanced Testing Techniques in Autoimmune Hemolytic Anemia/Role of Molecular Testing in Transfusion Medicine

Friday, Dec. 8, 2:05-3:20 pm
San Diego Convention Center, Room 28 A-D

Michael boeckh, MD, PhD

Scientific Workshop

New Treatments for CMV Reactivation after Hematopoietic Stem Cell Transplant

Presenter: Michael Boeckh, MD, PhD
Session: The Landscape of Viral Reactivation After Transplantation

Friday, Dec. 8, 3:33-4:13 pm
San Diego Convention Center, Room 8

Chaitra Ujjano, MD

Scientific Education

Dual Targeted Regimens for the Front-line Treatment of CLL

Presenter: Chaitra Ujjani
Session: How Do We Extend Survival for Patients with Chronic Lymphocytic Leukemia (CLL) in 2023?

Saturday, Dec. 9, 2:00-3:15 pm
San Diego Convention Center, Ballroom 20CD 

Marie Bleakley, MD, PhD, MMSC

Scientific Symposia

Alternate Immune Effector Cells

Presenter: Marie Bleakley, MD, PhD, MMSC
Presentation: Advances in TCR Based Therapeutics for Hematologic Malignancies

Saturday, Dec. 9, 3 pm
San Diego Convention Center, Room 6DE

Kate Markey, MD

Scientific Symposia

The Role of the Microbiota on Hemopoiesis and Immune Reconstitution after Therapy

Presenter: Kate Markey, MD
Session: The Impact of the Microbiota on Immunotherapy of Hematological Malignancies

Sunday, Dec. 10, 9:30-10:45 am
San Diego Convention Center, Room 25

Geoffrey Hill, MD, FACP, FRCPA

Meet the Blood Advances Editors

Blood Journals Studio

Panelist: Geoffrey Hill, MD, FACP, FRCPA

Monday, Dec. 11, 2023, 10-11 am
San Diego Convention Center, Hall A

Roland B. Walter, MD, PhD, MS

Symposia

Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular 

Moderator: Roland B. Walter, MD, PhD, MS
Presentation: Acute Myeloid Leukemias: Commercially Available Therapies, Excluding Transplantation and Cellular Immunotherapies: Refining Chemotherapy Regimens Plus/Minus MRD Evaluation to Optimize Outcomes in AML

Monday, Dec. 11, 2:45-4:15 pm
Marriot Marquis San Diego Marina, Grand Ballroom AB

Andrew J. Cowan, MD

Symposia

Health Services and Quality Improvement - Lymphoid Malignancies Program

Presenter: Andrew J. Cowan, MD
Presentation: Health Services and Quality Improvement Lymphoid Malignancies: Improving Processes and Outcomes in Plasma Cell Dyscrasias

Monday, Dec. 11, 2:45-4:15 pm
Marriott Marquis San Diego Marina, Grand Ballroom 2-4

Damian J. Green, MD

Symposia

Cellular Immunotherapies: Early Phase and Investigational Therapies Program

Presenter: Damian J. Green, MD
Presentation: Cellular Immunotherapies: Early Phase and Investigational Therapies: CAR-T Cell Therapies for Multiple Myeloma and B Cell Lymphomas

Monday, Dec. 11, 4:30-6 pm
San Diego Convention Center, Room 6A

Highlights of Fred Hutch Presentations at ASH

Saturday, December 9  |   Sunday, December 10  |  Monday, December 11

 

Saturday, December 9

BCMA-Directed Low Dose Alpha-Emitter Therapy Eliminates Minimal Residual Disease in a Multiple Myeloma Mouse Xenograft Model
Abstract No. 53
Presenter: Damian Green, MD
Saturday, Dec. 9, 10:30 am
Location: Manchester Grand Hyatt, Grand Hall D

Out-of-Pocket Costs and Financial Hardship Among Participants of the BMT CTN 1102 Study
Abstract No. 262
Presenter: Christopher T. Su, MD, MPH
Saturday, Dec. 9, 2:45 pm
Location: San Diego Convention Center, Hall A

Impact of Ibrutinib Dose Reduction on Duration of Therapy in Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Abstract No. 269
Presenter: Mazyar Shadman, MD MPH
Saturday, Dec. 9, 3 pm
Location: Marriott Marquis San Diego Marina, Pacific Ballroom Salons 21-22

CLEC2A Is a Novel AML-Restricted Immunotherapeutic Target Enriched in KMT2A-Rearranged Acute Myeloid Leukemia
Abstract No. 290
Presenter: Danielle C. Kirkey, MD
Saturday, Dec. 9, 4:15 pm
Location: San Diego Convention Center, Room 6CF

Microbiota-Specific T Cells Contribute to Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation
Abstract No. 345
Presenter: Albert C. Yeh, MD
Saturday, Dec. 9, 4:30 pm
Location: San Diego Convention Center, Room 7

Lisocabtagene Maraleucel (liso-cel) in R/R CLL/SLL: 24-Month Median Follow-up of TRANSCEND CLL 004
Abstract No. 330
Presenter: David G. Maloney, MD, PhD
Saturday, Dec. 9, 5:15 pm
Location: Manchester Grand Hyatt San Diego, Grand Hall D

Preclinical Characterization of the Anti-Leukemia Activity of the CD33/CD16/NKG2D Immune Modulating TriNKET® BMS-986357 (CC-96191)
Abstract No. 1431
Presenter: Magaret C. Lunn
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

LAMP5 Is an AML-Restricted Immunotherapeutic Target Enriched in High-Risk Acute Myeloid Leukemia
Abstract No. 1585
Presenter: Danielle C. Kirkey, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Intent to Treat Allogeneic Stem Cell Transplantation Outcomes in Relapsed/Refractory T-Cell Lymphomas
Abstract No. 1708
Presenter: Christina Poh, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Optimizing Siglec-8-Directed Immunotherapy for Eosinophilic and Mast Cell Disorders
Abstract No. 1781
Presenter: MGeorge S. Laszlo, PhD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Successful Treatment-Free Remission in Low- and Middle-Income Countries
Abstract No. 1808
Presenter: Jerald Radich, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Resistance to CD38 Antigen Targeted Therapy in Multiple Myeloma May Result from Underrecognized Chromosome 4 Gene Deletions
Abstract No. 1976
Presenter: Andrew J. Portuguese, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Trogocytosis May Attenuate the Efficacy of Anti-BCMA CAR T Cells Administered in Combination with γ-Secretase Inhibitor
Abstract No. 2083
Presenter: Pinar Ataca Atilla, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Factors Associated with Prolonged CRS and Neurotoxicity after Treatment with Axicabtagene Ciloleucel
Abstract No. 2126
Presenter: Aya Albitar, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Lisocabtagene Maraleucel Versus Axicabtagene Ciloleucel: Efficacy and Toxicity in a Real-World Setting
Abstract No. 2131
Presenter: Andrew J. Portuguese, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Machine Learning-Based Time-Series Clustering Identifies Archetypal Trajectories of Hematotoxicity after CAR T-Cell Therapy
Abstract No. 2143
Presenter: Emily C. Liang, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Total Body Irradiation Versus Chemotherapy-Only Conditioning in Autologous Hematopoietic Stem Cell Transplantation for Large B-Cell Lymphoma
Abstract No. 2224
Presenter: Maryam Ebadi, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

CD90-Targeted Cocal-Pseudotyped Lentivirus As a Robust Platform for Human HSC Gene Therapy
Abstract No. 2254
Presenter: Justin Thomas, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Shotgun Sequencing of Multi-Site Oral and Colonic Microbiota in Patients with AML: Site-Specific Patterns and Microbiota Decompartmentalization
Abstract No. 2273
Presenter: Armin Rashidi, MD, PhD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Rapid Clinical Mutation Screening for AML Using the Genexus Platform
Abstract No. 2288
Presenter: Jerald Radich, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Financial Toxicity and Time Toxicity in Multiple Myeloma: Prevalence, Predictors, and Impact on QOL
Abstract No. 2386
Presenter: Rahul Banerjee, MD, FACP
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Impaired Cognitive Function in Immune-TTP Is Better Predicted By Serum Thrombomodulin Than ADAMTS13 Activity: Results of a Longitudinal Multicenter Pilot Study
Abstract No. 2386
Presenter: Aaron Boothby, MD
Saturday, Dec. 9, 5:30-7:30 pm
Location: San Diego Convention Center, Halls G-H

Sunday, December 10

Efficient and Stable Makassar Base Editing in Nonhuman Primates
Abstract No. 484
Presenter: Stefan Radtke, PhD
Sunday, Dec. 10, 10:15 am
Location: San Diego Convention Center, Ballroom 20CD

Day +3/Day 0 Ferritin Ratio: A Simple Point-of-Care Index Predictive of Severe Immune Effector Cell-Associated Neurotoxicity Syndrome after CD19 CAR T-Cell Therapy
Abstract No. 3495
Presenter: Jennifer J. Huang, MD, PhD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

A Phase 2 Study of Nivolumab for Relapsed/Refractory Multiple Myeloma or Non-Hodgkin Lymphoma Following CAR-T Therapy
Abstract No. 3509
Presenter: Rahul Banerjee, MD, FACP
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Allogeneic Hematopoietic Cell Transplantation in the 7th Decade of Life and Beyond
Abstract No. 3608
Presenter: Mary-Elizabeth M. Percival, MD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Zinc Status Affects T Cell Reconstitution in Patients Receiving Naïve T Cell Depleted Allogeneic HSCT
Abstract No. 3562
Presenter: Lorenzo Iovino, MD, PhD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Testing the Limits of Endogenous Thymic Regeneration after HCT Conditioning
Abstract No. 33562
Presenter: Dante Dennis Acenas II
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Hematopoietic Stem Cell Transplantation (HCT) Conditioning Leads to NK Cell Cytotoxicity Limiting Endogenous Thymus Regeneration
Abstract No. 461
Presenter: David Granadier, BS
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Impact of Socioeconomic Disparities on Outcomes in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia
Abstract No. 3809
Presenter: Megan Othus, PhD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Elevated Metabolite Secretion Facilitates a Treg-Mediated Immunosuppressive Microenvironment in the Solid Tumor
Abstract No. 3458
Presenter: Sinéad Kinsella, MSc, PhD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Identifying a Relapse Signature in CBFB-MYH11 Acute Myeloid Leukemia
Abstract No. 2955
Presenter: Jack H Peplinski, BS
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Evaluation of ECOG Performance Status at Diagnosis and Relapse in Patients with Acute Myeloid Leukemia
Abstract No. 2844
Presenter: Carole Shaw 
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Prognostic Value of Copy Number Aberrations and Copy Neutral Loss of Heterozygosity in Acute Myeloid Leukemia
Abstract No. 2945
Presenter: Suravi Raychaudhuri, MD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Update for the ‘Watch’ Registry, a Real-World Observational Study Using Clonoseq® to Monitor MRD in Lymphoid Malignancies
Abstract No. 3777
Presenter: Andrew J. Cowan, MD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Heterogeneity of TP53 Mutations in Mantle Cell Lymphoma- Challenges in Risk Stratification and Subclassification
Abstract No. 3047
Presenter: Carrie I Ho, MD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Phase I Trial Combining Venetoclax with G-CSF, Cladribine, Cytarabine, and Mitoxantrone (CLAG-M) for Patients with High-Grade Myeloid Neoplasms
Abstract No. 2897
Presenter: Suravi Raychaudhuri, MD
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Binary Gender Differences in Quality of Life and Social Supports Among Individuals with Immune Thrombocytopenia (ITP): Data from the ITP Natural History Study Registry
Abstract No. 2592
Presenter: Terry Gernsheimer 
Sunday, Dec. 10, 6-8 pm
Location: San Diego Convention Center, Halls G-H

Monday, December 11

Integrative Genome and Transcriptome Sequencing Analysis Indicates Genetic and Epigenetic Dysregulation in DS-AML
Abstract No. 4306
Presenter: Rhonda E. Ries, MA
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML
Abstract No. 4306
Presenter: Rhonda E. Ries, MA
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Identification of a Relapse Signature in t(8;21) Pediatric AML
Abstract No. 4318
Presenter: Logan K. Wallace
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Identification of a Novel AML Patient Subset Sensitive to Venetoclax Using Matched Proteomics and Diverse Ex Vivo Models
Abstract No. 4338
Presenter: Derek Stirewalt, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Durable Remissions in Advanced Stage and Molecularly High Risk Untreated Classic Hodgkin Lymphoma with Pembrolizumab + AVD
Abstract No. 4429
Presenter: Ryan Lynch, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

A Phase 1 Study of Subcutaneous Rituximab Hyaluronidase Combined with Local Standard-of-Care Chemotherapy for the Treatment of Diffuse Large B-Cell Lymphoma in Uganda
Abstract No. 4467
Presenter: Henry Ddugnu, MD, PhD 
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Clinical Outcomes in Patients Treated with Both Covalent Btkis and Venetoclax and the Significance of Double-Refractory Status in Patients with CLL/SLL
Abstract No. 4650
Presenter: Laura Samples, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Predictors of Outcomes with Venetoclax-Based Treatment in Patients with Progressive Disease or Intolerance after Covalent BTK Inhibitors
Abstract No. 4656
Presenter: Laura Samples, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Potent and Target Specific Cytotoxicity of PRAME TCR Mimic CAR T Cells in KMT2A-Rearranged AML Patient-Derived Xenograft Model
Abstract No. 4821
Presenter: Danielle C. Kirkey, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Multispecific Hybrid T Cell Receptors for Sensitive Targeting of Cancer
Abstract No. 4822
Presenter: Sylvain Simon, PhD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Leukemia Blasts Induce NK-like Dysfunction in AML-Specific T Cells
Abstract No. 4849
Presenter: Francesco Mazziotta, MD, MPH
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Lymphocyte Reconstitution after Naïve T Cell-Depleted Hematopoietic Cell Transplantation
Abstract No. 4937
Presenter: Melinda Ann Biernacki, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Post Hematopoietic Cell Transplantation Maintenance Therapy with Low-Dose Azacitidine in a Pediatric Population with High-Risk Myeloid Neoplasms
Abstract No. 4956
Presenter: Emily Merkel, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Standard-of-Care Bortezomib Dosing in Multiple Myeloma: An International Survey of Physicians
Abstract No. 5073
Presenter: Rahul Banerjee, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Incidence and Management of COVID-19 Infections in Vaccinated Patients with CLL
Abstract No. 5149
Presenter: Chaitra S. Ujjani, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

Evaluating Patient-Reported Outcomes and Wearable Data Among Individuals with Relapsed/Refractory Multiple Myeloma
Abstract No. 5191
Presenter: Rahul Banerjee, MD
Monday, Dec. 11, 6-8 pm
Location: San Diego Convention Center, Hall G-H

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