Clinical Trials

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Searched for: Sarcoma. 22 results shown below.

Recombinant Interferon Gamma in Treating Patients With Soft Tissue Sarcoma

[Complete title: A Pilot Study to Test whether Systemic Interferon Gamma Increases Tumor Class I MHC Expression in Patients with Synovial Sarcoma and Myxoid / Round Cell Liposarcoma]
Principal Investigator: Seth Pollack
Study Number: 2705.00
Phase: Pilot

NY-ESO-1-specific T Cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy

[Complete title: A pilot trial of NY-ESO-1-specific T cells in patients with metastatic NY-ESO-1-expressing sarcomas receiving palliative radiation]
Principal Investigator: Seth Pollack
Study Number: 2721.00
Phase: I

Pazopanib Hydrochloride Followed By Chemotherapy and Surgery in Treating Patients With Soft Tissue Sarcoma

[Complete title: The Effect of Antiangiogenic Therapy with Pazopanib Prior to Preoperative Chemotherapy for Subjects with Extremity Soft Tissue Sarcomas: A Randomized Study to Evaluate Response by Imaging]
Principal Investigator: Darin Davidson
Study Number: 7487
Phase: Pilot

TLR4 Agonist GLA-SE and Radiation Therapy in Treating Patients With Metastatic Sarcoma

[Complete title: A Phase I Study to Determine the Safety of the Combination of Stable-Emulsion Formulation of Glucopyranosyl Lipid A (GLA-SE) with Radiation in Patients with Metastatic Sarcoma]
Principal Investigator: Seth Pollack
Study Number: 9145
Phase: I

Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors

[Complete title: Young Adult Cancer Survivor Network Study of the Essential Elements of Care (YA-EEC-14)]
Principal Investigator: K.Scott Baker
Study Number: 9161
Phase: II

Clinical Database for Sarcoma Patients (Sarcobase)
Principal Investigator: Doug Hawkins, MD
Study Number: CHMC-6009
Phase: NA

ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide in Patients With Previously Treated, Incurable Ewing Sarcoma

[Complete title: ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib, and Temozolomide in Patients with Previously Treated, Incurable Ewing Sarcoma]
Principal Investigator: Doug Hawkins, MD
Study Number: SC-6015
Phase: I

Construction of a Metastatic Osteosarcoma Tissue Microarray
Principal Investigator: Doug Hawkins, MD
Study Number: SC-B604

Analysis of Surgical Margins and Local Recurrence Risk in Patients with Osteosarcoma
Principal Investigator: Doug Hawkins, MD
Study Number: SC-B606

Genetic Risk Factors of Ewing Sarcoma
Principal Investigator: Doug Hawkins, MD
Study Number: SC-B611

NY-ESO-1 Specific T Cells After Cyclophosphamide in Treating Patients With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

[Complete title: A Study To Determine the Feasibility of Treating Synovial Sarcoma and Myxoid/ Round Cell Liposarcoma using Autologous NY-ESO-1 Specific CD8+ T Cells with Cyclophosphamide Pre-Conditioning but Without the Use of IL-2]
Principal Investigator: Seth Pollack
Study Number: 2720.00
Phase: I

Enrollment on the Childhood Cancer Research Network (CCRN) of the Children s Oncology Group

[Complete title: Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) and Local Data Collection]
Principal Investigator: Doug Hawkins, MD
Study Number: ACCRN07

BMN-673 and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

[Complete title: ADVL1411, PHASE 1/ 2 STUDY OF BMN 673 (IND# 121510), AN ORAL POLY(ADP-RIBOSE) POLYMERASE INHIBITOR, PLUS TEMOZOLOMIDE IN CHILDREN WITH REFRACTORY OR RECURRENT MALIGNANCIES]
Principal Investigator: Julie Park, MD
Study Number: ADVL1411
Phase: I/II

Collecting and Storing Biological Samples From Patients With Ewing Sarcoma

[Complete title: A Children’s Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens]
Principal Investigator: Doug Hawkins, MD
Study Number: AEWS07B1
Phase: NA

Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma

[Complete title: AEWS1031, A Phase III Randomized Trial of Adding Vincristine-topotecan-cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma]
Principal Investigator: Doug Hawkins, MD
Study Number: AEWS1031
Phase: III

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

[Complete title: AEWS1221, Randomized Phase II Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (AMG 479, NSC# 750008, IND# 120449) to Multiagent Chemotherapy for Patients with Newly Diagnosed Metastatic Ewing Sarcoma]
Principal Investigator: Doug Hawkins, MD
Study Number: AEWS1221
Phase: II

Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma

[Complete title: A Children’s Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens]
Principal Investigator: Doug Hawkins, MD
Study Number: AOST06B1
Phase: NA

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

[Complete title: Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613)]
Principal Investigator: Doug Hawkins, MD
Study Number: ARST1321
Phase: II

Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

[Complete title: A COG Soft Tissue Sarcoma Diagnosis, Biology, and Banking Protocol]
Principal Investigator: Doug Hawkins, MD
Study Number: D9902
Phase: NA

A Study to Provide Access to Trabectedin in Patients With Non L-type Soft Tissue Sarcoma Who Have Persistent or Recurrent Disease and Who Are Not Expected to Benefit From Currently Available Standard of Care Treatment

[Complete title: A Multicenter, Open-label Single-arm Study of YONDELIS® (trabectedin) for Subjects with Locally Advanced or Metastatic Soft Tissue Sarcoma Who Have Relapsed or Are Refractory to Standard of Care Treatment]
Principal Investigator: Edward Kim
Study Number: 20051530
Phase: III

A Phase 1b Safety Study of CMB305 (Sequentially Administered LV305 and G305) in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1

[Complete title: A Phase 1b Study Evaluating the Safety, Tolerability and Immunogenicity of CMB305 (Sequentially Administered LV305 and G305) in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1]
Principal Investigator: Seth Pollack
Study Number: 9290
Phase: I

Pazopanib Paediatric Phase II Trial Children's Oncology Group (COG) in Solid Tumors

[Complete title: ADVL1322, A Phase II Study of Pazopanib (GW786034, NSC# 737754) in Children, Adolescents and Young Adults with Refractory Solid Tumors]
Principal Investigator: Julie Park, MD
Study Number: ADVL1322
Phase: II

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  • Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.

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