List clinical trials by disease

Clinical Trials

List clinical trials by disease

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Searched for: Brain Cancer. 14 results shown below.
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma
Complete title: ACNS0332, Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients

Principal Investigator: Doug Hawkins, MD

Study Number: ACNS0332

Phase: III



Exploring Genetic Changes In Pediatric Brain Tumors

Principal Investigator: Sarah Leary

Study Number: SC-B904



Radiation Therapy With Concomitant and Adjuvant Temozolomide or Radiation Therapy With Adjuvant PCV or Temozolomide Alone in Treating Patients With Anaplastic Glioma
Complete title: Phase III Intergroup Study of Temozolomide Alone versus Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q Co-deleted Anaplastic Glioma

Principal Investigator: George Laramore, MD, PhD

Study Number: 8078

Phase: III



A Pilot RCT of the PRISM Intervention for AYAs With Cancer
Complete title: A Pilot Randomized Controlled Trial of the Promoting Resilience in Stress Management (PRISM) Intervention for Adolescents and Young Adults with Cancer

Principal Investigator: Abby Rosenberg

Study Number: SC-N114

Phase: Pilot



Enrollment on the Childhood Cancer Research Network (CCRN) of the Children s Oncology Group
Complete title: ACCRN07, Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) and Local Data Collection

Principal Investigator: Doug Hawkins, MD

Study Number: ACCRN07



A Study of Ramucirumab (LY3009806) in Children With Refractory Solid Tumors
Complete title: ADVL1416, A Phase 1 study of Ramucirumab, a Human Monoclonal Antibody Against the Vascular Endothelial Growth Factor-2 (VEGFR-2) Receptor in Children with Refractory Solid tumors, including CNS Tumors

Principal Investigator: Julie Park, MD

Study Number: ADVL1416

Phase: I



Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
Complete title: Phase I Study of CDK 4-6 Inhibitor PD-0332991 In Children With Recurrent, Progressive or Refractory Central Nervous System Tumors

Principal Investigator: Sarah Leary

Study Number: PBTC-042

Phase: I



PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Complete title: Phase II Study of everolimus for recurrent or progressive low-grade gliomas in children

Principal Investigator: Sarah Leary

Study Number: PNOC001

Phase: II



Vemurafenib in Children With Recurrent/Refractory BRAFV600E-mutant Gliomas
Complete title: Safety, Phase 0, and Pilot Efficacy Study of vemurafenib, an oral inhibitor of BRAFV600E, in Children and Young Adults with Recurrent/Refractory BRAFV600E-or BRAF Ins T mutant gliomas

Principal Investigator: Sarah Leary

Study Number: PNOC002

Phase: Pilot



A Study of ABT-414 in Subjects With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplification (Intellance1)
Complete title: A Randomized Placebo Controlled Phase 2b/3 Study of ABT-414 with Concurrent Chemoradiation and Adjuvant Temozolomide in Subjects with Newly Diagnosed Glioblastoma (GBM) with Epidermal Growth Factor Receptor (EGFR) Amplification (Intellance 1)

Principal Investigator: Lia Halasz

Study Number: 20151231

Phase: II/III



Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK1/2/3, ROS1, or ALK Gene Rearrangements (Fusions) (STARTRK-2)
Complete title: An Open-Label, Multicenter, Global Phase II Basket Study of Entrectinib for the Treatment of Patients with Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements

Principal Investigator: Gabriela Chiorean

Study Number: 20152369

Phase: II



Study of LOXO-101 in Subjects With NTRK Fusion Positive Solid Tumors (NAVIGATE)
Complete title: A Phase II Basket Study of the Oral TRK Inhibitor LOXO-101 in Subjects with NTRK Fusion-Positive Tumors

Principal Investigator: Christina Baik

Study Number: 20161101

Phase: I/II



A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
Complete title: SC-4003, BRF116013, Phase I/IIa, 2-Part, Multi-Center, Single-Arm, Open-Label Study to Determine the Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib in Children and Adolescent Subjects with Advanced BRAF V600-Mutation Positive Solid Tumors

Principal Investigator: Sarah Leary

Study Number: SC-4003

Phase: I/II



Phase I/II Study of MEK162 for Children With Ras/Raf Pathway Activated Tumors
Complete title: Phase I-II Study of MEK 162 for Children with Low-Grade Gliomas and Other Ras/Raf/ERK Pathway Activated Tumors

Principal Investigator: Sarah Leary

Study Number: SC-9012

Phase: I/II



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