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Complete title: Abatacept Combined with a Calcineurin Inhibitor and Methotrexate for Graft Versus Host Disease Prophylaxis: A Randomized Controlled Trial
|Research Study Number||2692.00|
|Principal Investigator||Leslie Kean|
Research Study Description
The investigators are doing this study to see if a new drug, abatacept, can be used together with a calcineurin inhibitor (cyclosporine or tacrolimus) and methotrexate to provide better protection against Acute Graft versus Host Disease (aGvHD) without causing more infections.
Funding Source - FDA OOPD
Eligibility Criteria (must meet the following to participate in this study)
Other eligibility criteria may apply.
Leukemia, Acute Lymphoblastic (ALL); Leukemia, Acute Myeloid (AML); Autoimmune Diseases; Hematologic Malignancies; Myelodysplastic Syndromes (MDS); Graft Versus Host Disease, Chronic (cGVHD); Graft Versus Host Disease (GVHD); Immune System Diseases
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