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Abatacept as GVHD Prophylaxis Phase 2

Complete title: Abatacept Combined with a Calcineurin Inhibitor and Methotrexate for Graft Versus Host Disease Prophylaxis: A Randomized Controlled Trial

Research Study Number       2692.00
Principal Investigator       Leslie Kean
Phase       Pilot

Look up trial at NIH

Research Study Description

This is a phase II multi-center, randomized, double blind, placebo-controlled trial.

The investigators are doing this study to see if a new drug, abatacept, can be used together with a calcineurin inhibitor (cyclosporine or tacrolimus) and methotrexate to provide better protection against Acute Graft versus Host Disease (aGvHD) without causing more infections.

Funding Source - FDA OOPD

Eligibility Criteria (must meet the following to participate in this study)

** For Eligibility information, please click on the "Look up trial at NIH" link above. **

Other eligibility criteria may apply.

Research Study Number       2692.00
Contact       Shauna Sinclair
Telephone       206/987-2553

Acute Lymphoid Leukemia (ALL); Acute Myeloid Leukemia (AML); Autoimmune Diseases; Hematologic Malignancies; Myelodysplastic and Myeloproliferative Syndromes (MDS and MPD); Chronic Graft Versus Host Disease (cGVHD)

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  • Talk to your health care providers first before making decisions about your health care.
  • Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.

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