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Complete title: A Phase I/II Study of Low Dose Cytarabine and Lintuzumab-Ac225 in Older Patients with Untreated Acute Myeloid Leukemia
|Research Study Number||2572.00|
|Principal Investigator||John Pagel, MD, PhD|
Research Study Description
The goal of the Phase 2 part of this study is to learn if Lintuzumab-Ac225 and cytarabine can control AML. The safety of this drug combination will also be studied.
Lintuzumab-Ac225 is designed to deliver radiation therapy directly inside leukemia cells without giving any radiation to the surrounding normal cells.
Cytarabine is designed to insert itself into DNA (genetic material) of cancer cells and stop the DNA from repairing itself.
Eligibility Criteria (must meet the following to participate in this study)
Other eligibility criteria may apply.
Leukemia, Acute Myeloid (AML); Hematologic Malignancies
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