Return to search results.
Complete title: Molecular Correlates of Sensitivity and Resistance to Therapy in Genitourinary Malignancy
|Research Study Number||6932|
|Principal Investigator||Robert Montgomery, MD|
Research Study Description
Eligibility Criteria (must meet the following to participate in this study)
Genders Eligible for Study: Male
Accepts Healthy Volunteers: Yes
Sampling Method: Non-Probability Sample
Patients with prostate or bladder/urothelial cancer treated in genitourinary oncology practices at University of Washington Medical Center, Seattle Cancer care Alliance and Harborview Medical Center and healthy controls
- Patients with localized and/or metastatic bladder/urothelial or prostate cancer who have disease in the primary organ, biopsy accessible bone metastases (collaborating radiologists will determine if bone metastasis is appropriate for biopsy) or soft tissue metastases are eligible; men and women without cancer are eligible to have blood or normal tissue collected if acquired as part of non-research procedures (e.g. transurethral resection of the prostate or bladder); in patients without malignancy, no additional tissue beyond that necessary for care will be procured
- Ability to adequately understand and give informed consent
- Local or metastatic disease to soft tissue or bone at sites accessible to biopsy with minimal risk of complications
- Platelet count > 50,000
- White blood cell (WBC) > 1,500
- Hemoglobin (Hgb) > 8.0
- International normalized ratio (INR) < 1.5
- Partial thromboplastin time (PTT) < 45
- No history of excessive unexplained bleeding from previous surgery
Other eligibility criteria may apply.
Exclusions (conditions that would prevent participation in this study)
- Serious or uncontrolled infection
- Treatment with a vascular endothelial growth factor (VEGF) inhibitor (such as Avastin) within the past 28 days
Other exclusion criteria may apply.
Genitourinary Cancer; Prostate Cancer; Solid Tumors
Disclaimer: We update this information regularly. However, what you read today may not be completely up to date.