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Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia (Interfant06)

Complete title: Interfant 06: International Collaborative Treatment Protocol For Infants Under One Year with Acute Lymphoblastic Leukemia or Biphenotypic Leukemia

Research Study Number       SC-2006
    
Principal Investigator       Rebecca Gardner, MD
    
Phase       III

Look up trial at NIH

Research Study Description

RATIONALE: Giving chemotherapy before a donor stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted cells from a donor can make an immune response against the body's normal cells. Giving cyclosporine, methotrexate, leucovorin, and antithymocyte globulin before and after transplant may stop this from happening. It is not yet known which treatment regimen is most effective in treating acute leukemia.

PURPOSE: This randomized clinical trial is studying how well different therapies work in treating infants with newly diagnosed acute leukemia.

Eligibility Criteria (must meet the following to participate in this study)

** For Eligibility information, please click on the "Look up trial at NIH" link above. **

Other eligibility criteria may apply.



Research Study Number       SC-2006
    
Contact       Rebecca Gardner, MD
    
Telephone       206/987-2106
    
E-mail      
    
   

Keywords
Leukemia, Acute Lymphoblastic (ALL); Hematologic Malignancies; Leukemia; Pediatric Cancers, Miscellaneous

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