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Clinical Trial Detail

A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat

Complete title: Phase 1b, open-label, multi-center study to characterize the safety, tolerability and pharmacodynamics (PD) of PDR001 in combination with LCL161, everolimus (RAD001) or panobinostat (LBH589)

Research Study Number 20162431
Principal Investigator Jennifer Specht, MD
Phase I

Research Study Description

The purpose of this study is to combine the PDR001 checkpoint inhibitor with several agents with immunomodulatory activity to identify the doses and schedule for combination therapy and to preliminarily assess the safety, tolerability, pharmacological and clinical activity of these combinations.

Eligibility Criteria (must meet the following to participate in this study)

** For Eligibility information, please click on the "Look up trial at NIH" link above. **

Other eligibility criteria may apply.

Research Study Number 20162431
Contact Seattle Cancer Care Alliance Intake Office
Telephone 800-804-8824 / 206-606-1024

Keywords: Breast Cancer; Colon Cancer; Lung Cancer; Rectal Cancer; Lung Carcinoma, Non-Small-Cell (NSCLC); Carcinoma, Bronchogenic; Neoplasms, Glandular and Epithelial; Adenocarcinoma; Colorectal Neoplasms; Carcinoma; Solid Organ Transplant (SOT); Triple Negative Breast Neoplasms; Neoplasms, Respiratory Tract; Neoplasms, Thoracic; Gastrointestinal Diseases; Digestive System Diseases

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