Clinical Trial Detail

Clinical Trials

Clinical Trial Detail

Oral TRK Inhibitor LOXO-101 (Larotrectinib) for Treatment of Advanced Pediatric Solid or Primary Central Nervous System Tumors (SCOUT)

Complete title: SC-4012, LOXO-TRK-15003, Phase I Study of the Oral TRK Inhibitor LOXO-101 in Pediatric Patients with Advanced Solid or Primary Central Nervous System Tumors

Research Study Number SC-4012
Principal Investigator Catherine Albert, MD
Phase I

Research Study Description

This is a multicenter, open label, Phase 1/2 study in pediatric patients with advanced solid or primary CNS tumors. LOXO-101 (larotrectinib) will be administered orally (PO) twice daily (BID), with the dose adjusted by body surface area (BSA).

Eligibility Criteria (must meet the following to participate in this study)

** For Eligibility information, please click on the "Look up trial at NIH" link above. **

Other eligibility criteria may apply.

Research Study Number SC-4012
Contact Advanced Therapeutics Study Line
Telephone 206/987-2553

Keywords: Central Nervous System (CNS); Pediatric Cancers, Miscellaneous; Solid Tumors; Neoplasms; Nervous System Diseases; Fibrosarcoma

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