Clinical Trial Detail

Clinical Trials

Clinical Trial Detail

Safety Study of SEA-CD40 in Cancer Patients

Complete title: A Phase 1, Open-Label, Dose-Escalation Study of SEA-CD40 in Adult Patients with Advanced Malignancies

Research Study Number 20150420
Principal Investigator Andrew Coveler, MD
Phase I

Research Study Description

This study will examine the safety profile of SEA-CD40. The study will test increasing doses of SEA-CD40 given at least every 3 weeks to small groups of patients. The goal is to find the highest dose of SEA-CD40 that can be given to patients that does not cause unacceptable side effects. The pharmacokinetics, pharmacodynamic effects, biomarkers of response, and antitumor activity of SEA-CD40 will also be evaluated.

Eligibility Criteria (must meet the following to participate in this study)

** For Eligibility information, please click on the "Look up trial at NIH" link above. **

Other eligibility criteria may apply.

Research Study Number 20150420
Contact Seattle Cancer Care Alliance Intake Office
Telephone 800-804-8824 / 206-606-1024

Keywords: Bladder Cancer; Breast Cancer; Esophageal Cancer; Gastrointestinal Cancer; Gynecological Cancer; Head and Neck Cancer; Hematologic Malignancies; Lymphoma, Hodgkin; Kidney Cancer; Lung Cancer; Lymphoma; Lymphoproliferative Disorders; Melanoma; Lymphoma, Non-Hodgkin (NHL); Solid Tumors; Lung Carcinoma, Non-Small-Cell (NSCLC); Carcinoma, Bronchogenic; Lymphoma, B-Cell; Carcinoma, Squamous Cell; Neoplasms, Glandular and Epithelial; Lymphoma, Follicular; Carcinoma; Neoplasms, Squamous Cell; Lymphoma, Large B-Cell, Diffuse; Immune System Diseases; Neoplasms, Bronchial; Immunotherapy; Neoplasms, Respiratory Tract; Neoplasms, Thoracic; Esophageal Diseases; Gastrointestinal Diseases; Pathologic Processes; Neoplasm Metastasis

Disclaimer: We update this information regularly. However, what you read today may not be completely up to date.

Please remember:

  • Talk to your health care providers first before making decisions about your health care.
  • Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.

Subscribe to an RSS feed of all trials