Basic Sciences Job Openings

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8 Found open positions

Post-Doctoral Research Fellow

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 13950

Overview

Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s Hospital, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference. Research from its Basic Sciences Division, is the foundation for ultimately understanding the causes of — and developing the treatments for — human disease.

Responsibilities

A postdoctoral position for recent PhD graduates is available in a lab in the Basic Sciences Division to study the function and evolution of centromeric proteins and satellite DNA in Drosophila.

Qualifications

Recent PhD degree. A strong foundation in molecular and cell biology. Strong background and familiarity with analysis of PacBio assembly of satellite DNA for analysis of centromeres and Y chromosomes is preferred. Experience in Drosophila genetics is required. Candidates need to be highly motivated and well-organized individuals who think independently but enjoy working as part of a dynamic and collaborative team. Excellent verbal and written communication skills.  Salary will be in line with the NIH pay scale.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Post-Doctoral Research Fellow, Cell and Developmental Biology

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13408

Overview

Cures Start Here. Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Laboratories in the Basic Sciences Division investigate diverse areas of molecular, computational, cellular, developmental, evolutionary and structural biology, metabolism, virology and immunity. We utilize a broad range of experimental and computational approaches and model systems. Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources, including core resources for imaging, proteomics, genomics, flow cytometry, high content screening, and small animal research. Frequent meetings and external seminars provide many opportunities for inter-lab collaborations. Careers Start Here.

Responsibilities

The Cooper lab in the Basic Sciences Division at the Fred Hutchinson Cancer Research Center is seeking new postdoctoral fellows. The Cooper lab has a demonstrated history of high impact studies of signal transduction mechanisms associated with mammalian cell migration in cell culture and in vivo model systems.


Potential projects include: investigating the interplay between tyrosine phosphorylation and ubiquitylation in cell migration; the in vivo roles of Cullin 5 ubiquitin ligase complexes; the non-adhesive functions of cadherins in cancer and development; and the dynamics of focal adhesion proteins. We are particularly interested in using live imaging of engineered cells to understand the sequence of events in cellular adhesions. Specifically, we want to know how focal adhesion turnover is regulated differently at the leading edge from under the cell body. What are the signals and how are they relayed to the adhesions? Candidates will be encouraged to build on these ideas and develop new directions for their research projects

Qualifications

Successful applicants will hold a PhD or MD and have extensive experience and interest in cell and/or developmental biology. In addition, applicants should have a 2+ years of experience working on projects in mammalian molecular, cellular or developmental biology. Hands on experience with cell imaging or murine developmental biology is desirable. The candidate should be enthusiastic, scientifically rigorous and inquisitive. Since the Cooper lab is small, the candidate will need the technical skills, confidence and drive it takes to start new directions. The candidate will be responsible for all aspects of their research project. They must be able to function independently and also be highly collaborative. Excellent written and verbal communication skills are essential.

 

To apply please submit your CV, a cover letter detailing your research interests and suitability for this position, and the names of at least two references.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Post-Doctoral Research Fellow, Mechanisms of Eukaryotic Transcription

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13632

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

The Hahn laboratory in the Division of Basic Sciences has an immediate opening for a Postdoctoral Associate to investigate mechanisms of transcriptional regulation using yeast as a model system. Potential research projects include studies on the mechanisms of transcription activators and the genome-wide roles of transcription coactivators and regulatory factors. A variety of approaches such as genomics, molecular genetics, biochemistry and computational biology will be utilized. The precise topic of the research project will be determined jointly with the candidate and candidates that display initiative and independence will be given priority.

Qualifications

PhD in either molecular and cellular biology, biochemistry, biophysics, or related fields with ideally 0-2 years of postdoctoral experience. Preferred candidates will have experience in molecular biology and biochemistry, next generation sequencing data analysis and experimentation (e.g., ChIP-seq, RNA-seq, etc.), and experience with Python and/or R.  Published evidence of productivity and creativity and strong analytical and interpersonal skills are required. The successful candidate will have the ability to work both independently and in a highly collaborative environment. 

 

To apply, please submit a CV and a cover letter that describes your research accomplishments as well as your interest in the Hahn laboratory research program. 

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Post-Doctoral Research Fellow, Molecular Neuroscience

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 12832

Overview

Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Laboratories in the Basic Sciences Division investigate diverse areas of molecular, computational, cellular, developmental, evolutionary and structural biology, metabolism, virology and immunity. We utilize a broad range of experimental and computational approaches and model systems. Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources, including core resources for imaging, proteomics, genomics, flow cytometry, high content screening, and small animal research. Frequent meetings and external seminars provide many opportunities for inter-lab collaborations.  

 

A highly motivated Post-Doctoral Fellow is sought to carry out research in the laboratory of Dr. Linda Buck at Fred Hutchinson Cancer Research Center in Seattle, WA.

 

The Buck Lab studies the molecular mechanisms and neural circuits that underlie the sense of smell and instinctive odor responses. It is interested in how the olfactory system detects myriad environmental chemicals and how the brain translates those chemicals into diverse odor perceptions, hormonal alterations, and instinctive behaviors.  It is also interested in neural mechanisms that underlie stress.  Illumination of the neural circuits underpinning these and related effects may provide clues to those affected in certain human disorders, particularly those involving stress, fear, and appetite.  The lab is particularly interested in using cutting edge technologies, such as single cell genomics, for dissecting the composition of complex neural networks.

Responsibilities

The fellow will be responsible for developing and executing a project related to current and future interests of the lab, as determined by discussions with Dr. Buck. The successful candidate will be an individual who is enthusiastic about science and is capable of independent research.

Qualifications

Required

  • PhD in molecular and cell biology or molecular neuroscience
  • Excellent knowledge of fundamental molecular and cell biology
  • Experience using molecular techniques for cloning and for analysis of nucleic acids and proteins
  • Experience using immunohistochemistry and/or in situ hybridization for analyses of gene expression


Preferred

  • Experience with RNA sequencing and bioinformatics
    • Experience in murine breeding and genotyping
  • Knowledge of neuroscience

To apply, please submit your CV, a cover letter describing your research experience and interests and contact information for three references. 

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Post-Doctoral Research Fellow, Shou Laboratory

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13628

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


A quantitative biology laboratory in the Division of Basic Sciences is seeking a highly motivated post-doctoral fellow.  Our lab provides a wonderful opportunity for developing an interdisciplinary research style that bridges chemistry/physics with biology.

Responsibilities

We are interested in using experimental biology, quantitative measurements, and mathematical modeling to examine microbial communities. For example, how might different microbial species interact with each other in a community to allow the community to carry out a function that would have otherwise been impossible? How might the presence of interacting partners influence the evolutionary trajectories of microbes? How might we effectively manipulate community functions? More information about the group may be found at honeycomb.fhcrc.org.

Qualifications

A Ph.D. in biology or in a related scientific discipline such as physics or engineering is required.

 

The successful candidate should have a strong background in biology, physics and/or engineering, ideally with expertise in both experiments and mathematical modeling. Our lab provides a wonderful opportunity for developing an interdisciplinary research style that bridges chemistry/physics with biology. 

 

To apply, please submit a CV, a cover letter stating your long-term goal, and a list of professional references.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Research Technician II, Quantitative Biology

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 11700

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

You are invited to apply for a position at the quantitative biology group in the Basic Sciences Division at Fred Hutch. We are interested in using experimental biology to quantitatively examine “cooperation,” because cooperation can be found virtually everywhere: between different cell types (e.g. our body), different individuals (e.g. ant colonies), or different species (e.g. flower-pollinator symbiosis). How can cooperation survive the invasion of cheaters that take but not give? How does cooperation evolve? We plan to study cooperation initially using an engineered system in which two complementary types of yeast cells can only survive when both types are present.

Responsibilities

The incumbent will perform a project related to evolution.  The incumbent will also be responsible for making common reagents for the lab and participating in daily activities and duties of the lab.  Finally, the incumbent will aid in the completion of other ongoing projects in the lab as needed.  The incumbent will have opportunities to present substantial research results at conferences and gain authorship in research articles.

Qualifications

A bachelor's degree is required and at least two years of laboratory experience. Strong quantitative skills including basic (high school) mathematics knowledge are required as is the ability to learn new things and to be highly organized. Comfort with computer programming and the ability to quantitatively analyze datasets independently is a big plus.

 

Applicants must submit a cover letter (stating why you are interested in the position and your educational/career goals), resume, at least one reference letter from your primary research adviser and the contact information for two other professional references.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Scientific Communications Liaison

FH Basic Sciences Division
Category: Communications and Marketing
Seattle, WA, US
Job ID: 13563

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


The Division of Basic Sciences is seeking an energetic, engaging and knowledgeable Scientific Communications Liaison with a scientific background and research experience to complement strong communications skills and expertise in content creation and distribution. This role requires the ability to translate and communicate scientific concepts to a variety of audiences, including scientific experts, business leaders, donors and the general public.

 

While the position will be within the Division, the successful applicant will work closely with the Communications and Marketing and Philanthropy departments and within Fred Hutch guidelines to ensure coordination in the broader context of the Center mission. The Communications Liaison will report to the Senior Operations Director of the Division of Basic Sciences and work with all faculty within the division to communicate research findings to both scientific and lay audiences.

Responsibilities

Responsibilities and essential job functions include but are not limited to the following:

  • Writing scientific content about past and current research in the Division to assist with various activities. For example, this will include writing relevant copy to assist with nominations for awards for faculty and trainees, and writing reports on the use of philanthropic funds.
  • Create and maintain digital scientific portfolios and career milestones for each faculty member within the Division.
  • Contribute scientific content for Division of Basic Sciences website and individual lab websites. This includes creating copy, participation in reviews and redesigns of sites as needed and assuring site content is current.
  • Develop and share content on behalf of Basic Science Division on social media, working within Fred Hutch guidelines, to keep scientists and the public aware of activities within the Division. Currently this includes a Twitter account and may include other social media sites such as Facebook.
  • Attending major scientific seminars given by faculty and trainees in the Division of Basic Sciences to stay up to date on the latest research areas.

 

Additional responsibilities may include:

  • Creating and maintaining current and accurate Wikipedia pages for eligible faculty and the Division.
  • Working with BSD scientists to develop slides and other presentation materials in support of internal talks, conference presentations and symposium discussions.
  • Producing communications materials to promote visiting scientists and symposiums.
  • Creating additional content for visual monitors in the common areas of the division.
  • Planning content and developing visions for short videos that will highlight how basic research is critical to solving scientific problems, breaking down barriers in cancer research, and developing key technologies that drive science forward. Manage external vendor relationships to support quality production and delivery of these videos.
  • Assisting with other scientific writing needs to promote the basic sciences at Fred Hutch as needed, such as assembling content for external scientific advisory board meetings.
  • Contribute to proposals as needed by writing sections relevant to BSD research for cross-Divisional work such as on program project or training grant proposals or requests for funding to philanthropy sources.

Qualifications

Experience

  • Preferred candidates have a doctorate in a biological discipline or undergraduate/masters degree with extensive research experience
  • Degree or graduate certificate in communications or scientific communications preferred
  • Experience with scientific writing for a general audience
  • Demonstrated ability to communicate science to a technical audience


Knowledge, Skills and Abilities

  • A passion for science and storytelling
  • Ability to read scientific articles and summarize key content for technical and lay audiences
  • Ability to envision and articulate how scientific content can be presented and distributed to a variety of audiences.
  • Ability to broadly engage in scientific communication on various topics
  • Interested in disseminating scientific knowledge to the public
  • Demonstrated ability to develop, manage, adapt and deliver engaging scientific content. Proven ability to translate complex source material into compelling content for donor or lay audiences.
  • Ability and interest in using social media to promote scientific findings
  • Comfortable with scientific discussion
  • Ability to handle confidential and sensitive information
  • Project management experience and demonstrated ability to work effectively on concurrent, diverse projects while maintaining strong attention to detail
  • Demonstrated ability to set and meet deadlines

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

Staff Scientist, Molecular and Behavioral Neuroscience

FH Basic Sciences Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 12023

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
 
A highly motivated and experienced Staff Scientist is sought to carry out research in the laboratory of Dr. Linda Buck at Fred Hutchinson Cancer Research Center in Seattle, WA.

The Buck Lab studies the molecular mechanisms and neural circuits that underlie the sense of smell and instinctive odor responses. It is interested in how the olfactory system detects myriad environmental chemicals and how the brain translates those chemicals into diverse odor perceptions, hormonal alterations, and instinctive behaviors. Illumination of the neural circuits underpinning these and related effects may provide clues to those affected in certain human disorders, particularly those involving stress, fear, and appetite.

Responsibilities

  • Conduct research independently as well as contributing to research being done by other team members as needed
  • Research will focus on one or more research interests of the lab
  • Breed and genotype transgenic murine for specific projects
  • Prepare and analyze tissue sections for mRNA and protein expression using standard techniques utilized in the lab
  • Clone and analyze DNA for use as probes
  • Conduct experiments to analyze murine behavior
  • Prepare graphs and images of research results for presentation and publication
  • Present results obtained in group meetings

Qualifications

Minimum

  • PhD in molecular and cell biology or molecular neuroscience
  • At least five years of post-doctoral research experience
  • Excellent knowledge of fundamental molecular and cell biology
  • Experience using molecular techniques for cloning and for analysis of nucleic acids and proteins
  • Experience in murine breeding and genotyping
  • Experience in preparing tissue sections and analyzing them using immunohistochemistry and in situ hybridization


Preferred

  • Knowledge of neuroscience
  • Experience analyzing murine behavior
  • Experience with RNA sequencing and bioinformatics is a plus  

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

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