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Stories tagged 'Mary Flowers'

What’s new in combatting chronic graft-vs.-host disease

Decades after the development of bone marrow transplant, researchers are making headway against one of its most common and deadly side effects

April 2, 2018 | By Rachel Tompa / Fred Hutch News Service

Up to 40% of transplant recipients develop chronic graft-vs.-host disease, which can last for years. But chronic GVHD is treatable, and new therapies and preventive measures are arriving and being tested in trials.

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‘How do you thank someone for saving your life?’

Stem cell donor, recipient meet each other – and researchers who made transplant possible

April 29, 2015 | By Linda Dahlstrom / Fred Hutch News Service

Leukemia survivor Mark Tose had one burning question for Dr. Mary Flowers: How much of the connection he feels with the donor for the transplant that saved his life is because they were biologically a perfect match — or is something else at play? "It feels like we've known each other forever," he said.

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Life with graft-vs.-host disease: When the transplant is just the beginning

How researchers are trying to combat this common, often debilitating side effect of treatment

April 21, 2015 | By Rachel Tompa / Fred Hutch News Service

Up to 70 percent of transplant recipients, such as Greg Grappone, develop acute graft-vs.-host disease, which crops up within the first few months of treatment, and 40 percent get chronic GVHD, the form that appears more than 100 days post-transplant. As the name implies, the chronic condition can last for years — or a lifetime — and its symptoms range from mildly annoying to disabling to life-threatening.

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