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Stories tagged 'Deborah Donnell'

HIV prevention gains bring hope — and challenges

Injectable PrEP and other options are in the pipeline, and that makes clinical trials more complicated

Oct. 14, 2016 | By Mary Engel / Fred Hutch News Service

An injectable form of PrEP and other options are in the pipeline as the HIV field enters a new era of prevention. But such advances, as welcome as they are, come with a twist: They complicate the task of designing the clinical trials needed to test additional tools. Fred Hutch's Dr. Deborah Donnell explains.

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CDC recommends daily pill for those at high risk for HIV

Researchers work on long-lasting injectable drug; vaccine still ‘the holy grail’

May 15, 2014 | By Mary Engel

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Six-month drug regimen cuts HIV risk for breastfeeding infants

SCHARP data shows longer nevirapine treatment reduces infection by half for babies with HIV-infected mothers, 75 percent for infants of untreated moms

March 14, 2011

Giving breastfeeding infants of HIV-infected mothers a daily dose of the antiretroviral drug nevirapine for six months halved the risk of HIV transmission to the infants at age 6 months compared with giving infants the drug daily for six weeks, according to preliminary clinical trial data presented March 2 at the Retroviruses and Opportunistic Infections conference in Boston.

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Study shows ART lowers HIV transmission

Antiretroviral therapy associated with 92 percent decreased risk of HIV transmission among HIV-1 discordant couples in large, multinational study

June 1, 2010

Research led by Dr. Deborah Donnell of the Vaccine and Infectious Disease Institute at the Fred Hutchinson Cancer Research Center has found that treating HIV-infected persons with antiretroviral therapy (ART) reduces HIV transmission to their sexual partners by more than 90 percent.

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The challenge of nevirapine resistance

Anthony Mwatha finds mothers and infants with some HIV subtypes show increased resistance to drug used to prevent perinatal transmission of HIV in developing countries

Feb. 2, 2006 | By JOEL DAHMS

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