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Stories tagged 'targeted t cell immunotherapy'

New insights into CAR T-cell therapy's potential side effects

Detailed study of cytokine release syndrome and neurologic toxicities could help make emerging cancer immunotherapies safer

Dec. 11, 2017 | By Fred Hutch staff

Detailed studies of two potential side effects of an emerging cancer immunotherapy could eventually help make this strategy, CAR T-cell therapy, safer for patients. The studies examined cytokine release syndrome and neurologic toxicities.

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Dissolving implant could bring immunotherapy to solid tumors

A biopolymer sponge delivers cancer-shrinking T-cell therapy in preclinical study

April 24, 2017 | By Sabrina Richards / Fred Hutch News Service

A dissolving scaffold developed by Dr. Matthias Stephan delivers engineered anti-tumor immune cells to crowded masses of tumor cells and recruits the native immune system to mount a second-wave attack on the cancer.

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Tiny tech reprograms immune cells to fight cancer

Nanoparticles turn immune cells into leukemia-fighting powerhouses while they’re still inside the body

April 17, 2017 | By Sabrina Richards / Fred Hutch News Service

Dr. Matthias Stephan has designed nanoparticles that have the potential to make cellular immunotherapy quicker, cheaper, easier to administer and more widely available, by carrying anti-cancer genes to immune cells still inside the body.

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Immunotherapy for ovarian cancer shows promise in mouse model, but hurdles remain

‘Tumor microenvironment’ poses unique challenges for T-cell therapy in solid tumors

April 4, 2017 | By Rachel Tompa / Fred Hutch News Service

A major roadblock to adopting T-cell therapy to solid tumors is what’s known as the tumor microenvironment, the local milieu of non-cancerous cells and molecules in and around the tumor. Fred Hutch researcher Dr. Kristin Anderson and her colleagues in Dr. Phil Greenberg's lab are working to overcome those barriers.

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What's new in blood diseases

Four things to watch from the 2016 annual meeting of the American Society of Hematology

Dec. 20, 2016 | By Susan Keown / Fred Hutch News Service

For a few days earlier this month, a small city’s-worth of health professionals and researchers from nations across the globe converged for the world’s biggest conference in hematology. Fred Hutch News Service was on the ground at the annual meeting of the American Society of Hematology Dec. 3-6 in San Diego, California. From immunotherapy for advanced blood cancers to new approaches to treating sickle cell disease, here’s our top four things to watch from the meeting.

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Fred Hutch opens first-of-its kind Bezos Family Immunotherapy Clinic

Clinic will allow researchers to conduct twice as many immunotherapy trials, enable intensive patient monitoring to improve experimental therapies

Nov. 1, 2016 | By Fred Hutch News Service

The new clinic will allow researchers to conduct twice as many immunotherapy trials and enable intensive patient monitoring to improve experimental therapies.

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