Hutch News

Hutch News

Stories tagged 'Molecular basis of cancer '

Good News at Fred Hutch

Celebrating faculty and staff achievements

Dec. 21, 2017

When it comes to cancer, there’s no shortage of potential drug targets — many molecules are thrown out of whack when tumors develop. But finding a drug that specifically works against these aberrant molecules is another task entirely. Now, a group led by Fred Hutchinson Cancer Research Center scientists has designed a small protein from scratch that specifically blocks a protein known as TEAD that plays a role in many different cancers.

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Good News at Fred Hutch

Celebrating faculty and staff achievements

Dec. 7, 2017

Fred Hutch Pancreatic cancer researcher Dr. Sunil Hingorani has won a three-year, $1.8 million grant from the federal Cancer Moonshot program, the signature initiative of former Vice President Joseph Biden. Hingorani is one of six collaborators nationwide who received funding this fall for a new research consortium focused on the biological context of pancreatic tumors — such as nearby immune cells or blood vessels — which can have a major impact on a tumor’s vulnerability to treatment.

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Immune cells share their insides with tumors to promote cancer spread

New study in zebrafish and mice shows immune cells interact with melanoma and transfer their contents to spur metastasis

Dec. 4, 2017 | By Rachel Tompa / Fred Hutch News Service

A new study using mice and tiny transparent fish as models of human cancer, published in Developmental Cell, has shed light on the very first stages of metastasis in the skin cancer melanoma.

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Science without borders

At Fred Hutch and other U.S. research centers, a global village works to cure cancer and other diseases

Oct. 16, 2017 | By Mary Engel / Fred Hutch Research Center

Fred Hutch, like other major U.S. cancer research centers, attracts top scientists from around the world working to cure cancer, HIV and other diseases

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Good News at Fred Hutch

Celebrating faculty and staff achievements

Aug. 24, 2017

Fred Hutchinson Cancer Research Center bioengineer and cancer researcher Dr. Cyrus Ghajar has focused much of his work on what causes breast cancer cells to metastasize. Now, with the help of a new $1 million grant from the W.M. Keck Foundation, Ghajar and his team are hoping to crack open a mystery that has long puzzled scientists in the field: Why do metastatic cells, which can proliferate in many organs, nearly always fail to grow in skeletal muscles, which account for as much as half the body mass of an adult?

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Closing the breast cancer divide in sub-Saharan Africa

Clinical trial in Uganda will test alternative diagnostic tool and oral chemotherapy, study genetic differences

Aug. 15, 2017 | By Mary Engel / Fred Hutch News Service

Researchers from Fred Hutchinson Cancer Research Center and the Uganda Cancer Institute are launching a clinical study in the Ugandan capital Kampala that could change the way breast cancer in sub-Saharan Africa is diagnosed and treated.

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