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Stories tagged 'gvhd'

Where are they now?

Updates on five memorable people we profiled in 2015

Dec. 31, 2015 | By Fred Hutch News Service staff

Countless people generously shared their stories with us and the world this year. Today, we'll update you on some of the most memorable people we wrote about during 2015.

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Finding a better (mis)match

New way to pair blood stem cell donors with recipients promises to lower risk of potentially devastating transplant side effect

Aug. 28, 2015 | By Susan Keown / Fred Hutch News Service

Soon, many patients coming to Seattle for blood stem cell transplants will have a lower risk of a potentially life-threatening complication thanks to additional genetic testing, which will be built on findings published this month by a team of Fred Hutch researchers led by Dr. Effie Wang Petersdorf.

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Life with graft-vs.-host disease: When the transplant is just the beginning

How researchers are trying to combat this common, often debilitating side effect of treatment

April 21, 2015 | By Rachel Tompa / Fred Hutch News Service

Up to 70 percent of transplant recipients, such as Greg Grappone, develop acute graft-vs.-host disease, which crops up within the first few months of treatment, and 40 percent get chronic GVHD, the form that appears more than 100 days post-transplant. As the name implies, the chronic condition can last for years — or a lifetime — and its symptoms range from mildly annoying to disabling to life-threatening.

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Pediatric transplant pioneer Jean Sanders retires

Hutchinson Center researcher built the nation's pediatric transplant program over her four-decade career; symposium June 29 will celebrate her groundbreaking achievements that have saved thousands of young lives

June 11, 2012 | By Galen Motin Goff

When Dr. Jean Sanders retires this later this month, she will leave a four-decade legacy that built the nation’s pediatric transplant program. A June 29 symposium and reception will celebrate her groundbreaking career at the Fred Hutchinson Cancer Research Center.

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Gaining gastrointestinal GVHD control

Phase III clinical trial on drug therapy to combat graft-vs.-host disease in stem-cell patients shows significant reduction in deaths

Jan. 29, 2007 | By DEAN FORBES

Hutchinson Center researchers have developed a new drug therapy that significantly reduces death from gastrointestinal graft-vs.-host disease in allogeneic stem-cell transplant patients. By adding a widely used topical corticosteroid to the standard GVHD treatment, researchers found it kept the potentially deadly side effect in remission and reduced death by 46 percent one year after therapy.

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Bone marrow transplants option for children with acute lymphoblastic leukemia

Procedure works to fight most common childhood cancer in cases without related donors, says study by Woolfrey

April 4, 2002 | By Barbara Berg

Bone-marrow transplantation between tissue-matched, unrelated individuals is a viable option for young children with acute lymphoblastic leukemia (ALL), the most common form of childhood cancer.

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