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Stories tagged 'genetic mutation'

The lung cancer blame game

The shame, blame and stigma surrounding this deadly disease affects everything from patient follow-through to research funding

Nov. 21, 2017 | By Diane Mapes / Fred Hutch News Service

Most people know that lung cancer is an aggressive killer, triggered by everything from smoking to genetic mutations to environmental toxins. But more and more patients, doctors and researchers are pointing to another harmful influence contributing to the suffering, delayed diagnosis and possibly even early deaths of those hit with the disease: stigma.

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Reawakening the X chromosome: New possible therapeutic targets for Rett syndrome

Study points to potential reversal of rare childhood neurological disorder by reactivating silenced copy of the disease-linked gene

Jan. 30, 2017 | By Rachel Tompa / Fred Hutch News Service

A research team led by Fred Hutch's Dr. Antonio Bedalov have uncovered 30 genes that could, one day, serve as therapeutic targets to reverse Rett syndrome, a rare neurological disorder that affects primarily girls and women. The new findings are described in a study published today in the journal Proceedings of the National Academy of Sciences.

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Common genetic disorder linked to increased death rate from cancer drug

Researchers recommend ‘caution’ when using the chemotherapy busulfan in patients with Gilbert’s syndrome

Oct. 27, 2016 | By Susan Keown / Fred Hutch News Service

As many as one of every 10 people has Gilbert's syndrome, which is typically benign and has even been linked to long life. But new research suggests that busulfan, a bone marrow transplant drug, is extra risky in people with the condition.

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Separate rulebook for cellular powerhouses

A precise new technique reveals that our cells’ engines, mitochondria, unexpectedly shrug off DNA damage from toxic chemicals

Sept. 1, 2016 | By Sabrina Richards / Fred Hutch News Service

Surprisingly, instead of falling prey to DNA damage that would cause rampant genetic errors, mitochondria are somehow able to outrun this damage and keep their DNA error-free, scientists at Fred Hutch have shown.

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Good News at Fred Hutch

Celebrating faculty and staff achievements

June 30, 2016

Dr. Anne McTernan named to HHS Physical Activity Guidelines Advisory Committee; Dr. Harlan Robins mentoring two projects funded by Stand Up To Cancer

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Good News at Fred Hutch

Celebrating faculty and staff achievements

March 18, 2016

Dr. Soheil Meshinchi receives $250K from Alex’s Lemonade Stand Foundation for childhood cancer research ... and more Good News at Fred Hutch.

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