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Stories tagged 'gene expression'

Revealing a new way that cancer can evade immunotherapy — and, maybe, how to stop it

How a new technology solved a mystery and honors one man’s legacy

Sept. 24, 2018 | by Susan Keown / Fred Hutch News Service

Before his aggressive cancer took his life, he donated his tissue samples to research. Now scientists think that new insights from his cells could save lives.

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Tapscott team discovers genes, mechanisms of common muscular dystrophy

Discoveries may result in biomarker test for facioscapulohumeral muscular dystrophy, a disease that initially affects the skeletal muscles of the face, scapula and upper arms

Jan. 30, 2012 | By Dean Forbes

Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, an international team of researchers led by the Hutchinson Center's Dr. Stephen Tapscott has identified the genes and proteins that damage muscle cells, as well as the mechanisms that can cause the disease.

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Researchers identify genes that signal oral cancer spread

Discovery could lead to the development of a biomarker-based test in lieu of neck surgery

May 9, 2011 | By Dean Forbes

For the first time, Fred Hutchinson Cancer Research Center scientists have identified genes that signal when oral cancer has spread to lymph nodes in the neck. If confirmed by additional research, the discovery of this four-gene set could lead to the development of a biomarker-based test of the tumor that could help physicians determine whether oral squamous cell carcinoma has spread and therefore become more deadly. The findings appear in the April 15 issue of Clinical Cancer Research.

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